2'-deoxycytidine Analysis Service

2'-deoxycytidine is a fundamental nucleoside that forms part of DNA, where it pairs with guanine and plays a crucial role in the integrity and stability of genetic material. 2'-deoxycytidine is composed of a cytosine base attached to a deoxyribose sugar. This nucleoside is critical in DNA replication and repair, ensuring the accurate transmission of genetic information during cell division.

 



 

Figure 1. The Structure of 2'-deoxycytidine

 

2'-deoxycytidine serves not only as a building block of DNA but also as a participant in various biochemical pathways. It can be phosphorylated to form deoxycytidine triphosphate (dCTP), which is directly used by DNA polymerase during DNA synthesis. 2'-deoxycytidine also plays an essential role in epigenetic regulation when modified by cytosine methylation or hydroxymethylation, contributing to gene expression control, chromatin structure modulation, and genomic stability.

 

Alterations in 2'-deoxycytidine metabolism or modifications, such as those seen in DNA methylation (5-methylcytosine) or hydroxymethylation (5-hydroxymethylcytosine), have significant biological implications. Abnormal 2'-deoxycytidine modifications are often associated with various diseases, including cancer and developmental disorders. As a result, understanding and measuring the levels of 2'-deoxycytidine and its modified forms are critical for research in epigenetics, oncology, and developmental biology.

 

At MtoZ Biolabs, we offer a comprehensive 2'-deoxycytidine Analysis Service utilizing advanced LC-MS/MS systems, coupled with our optimized sample preparation and data analysis methods, ensuring the accurate quantification and analysis of 2'-deoxycytidine in various samples.

 

Analysis Workflow

 



 

Service Advantages

• Expertise in metabolomics and bioinformatics analysis
• State-of-the-art HPLC-MS/MS technology for accurate and sensitive detection of 2'-deoxycytidine
• Professional and efficient customer service
• Comprehensive report with both raw and analyzed data, along with a detailed explanation of the findings

 

Applications

Our 2'-deoxycytidine Analysis Service can be utilized in various fields, including but not limited to:

• Biological Research: Understanding the role of 2'-deoxycytidine in biological processes.
• Drug Development: Evaluating the impact of potential drugs on 2'-deoxycytidine metabolism.
• Clinical Diagnostics: Investigating the relationship between 2'-deoxycytidine levels and disease states.

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice.

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Comprehensive Information on 2'-deoxycytidine

4. Raw Data

5. Custom Analysis Report

 

Let MtoZ Biolabs help you in your research journey. For more information about our 2'-deoxycytidine Analysis Service, please contact us.