17α-Hydroxypregnenolone Analysis Service
- Discovery of new biomarkers for various diseases
- Enhancing accuracy in disease diagnosis
- Accelerating the discovery of innovative therapeutics
- Understanding disease mechanisms in-depth
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
17α-Hydroxypregnenolone is an important steroid hormone intermediate belonging to the pregnenolone class. Its structural feature is a hydroxyl group at the C17 position, which gives it distinct biological activity. 17α-Hydroxypregnenolone is primarily synthesized from cholesterol in the adrenal cortex and gonads through the action of 17α-hydroxylase. It serves as a key intermediate in the steroid hormone synthesis pathway, and can be further converted into dehydroepiandrosterone (DHEA) or 17α-hydroxyprogesterone, both of which play crucial roles in gonadal function, stress response, and glucocorticoid regulation. Studies have shown that abnormal levels of 17α-hydroxypregnenolone are closely associated with various endocrine disorders, including congenital adrenal hyperplasia (CAH) and other adrenal dysfunctions. Accurate measurement of this metabolite allows researchers to better understand its role in endocrine regulation, providing important insights for the diagnosis and treatment of related diseases. Additionally, 17α-hydroxypregnenolone can serve as a potential biomarker for assessing adrenal cortex function and steroid metabolism pathways. Using highly sensitive mass spectrometry techniques, the concentration of 17α-hydroxypregnenolone in blood or urine can be precisely measured, providing critical data for clinical research and personalized medicine. This helps to reveal the dynamic changes of this molecule in various physiological and pathological conditions, opening new avenues for early screening and targeted therapy of hormone-related diseases.
Figure 1. The Structure of 17α-Hydroxypregnenolone
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of 17α-hydroxypregnenolone. We ensure the accuracy of the quantification of 17α-hydroxypregnenolone and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you are interested in our 17α-hydroxypregnenolone analysis service, please feel free to contact us at any time, and we will be fully committed to providing you with high-quality analytical services and technical support.
Analysis Workflow
Service Advantages
1. Advance Analysis Platform: MtoZ Biolabs established an advanced 17α-hydroxypregnenolone analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all 17α-hydroxypregnenolone analysis data, delivering clients a detailed and comprehensive data report.
4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. For each sample, more than three materials of the same condition must be selected.
2. Sample Volume
3. Sample Preservation
Store at -80°C to ensure stability.
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details （Materials, Instruments and Methods,etc.）
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 17α-Hydroxypregnenolone Analysis
4. Raw Data
5. Custom Analysis Report
Through our 17α-hydroxypregnenolone analysis service, our aim is to expedite your research and product development by offering accurate and trustworthy results.
How to order?
