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    17α-Estradiol Analysis Service

      17α-Estradiol is a naturally occurring estrogenic steroid hormone, structurally similar to 17β-estradiol, but its α-configuration at the C17 position gives it different biological activity. 17α-Estradiol has relatively weaker estrogenic activity and primarily plays a role in reproductive organs. It can be secreted by the ovaries or produced through other hormone metabolic pathways. Although its activity is lower than that of 17β-estradiol, 17α-estradiol still plays specific roles in regulating physiological functions, particularly in areas such as anti-aging, neuroprotection, and glucose-lipid metabolism regulation. In recent years, research on 17α-estradiol has increased, with particular focus on its potential role in aging-related diseases, neurodegenerative conditions, and metabolic disorders. Studies suggest that 17α-estradiol may exert neuroprotective effects by regulating apoptosis and inflammatory responses. Additionally, its regulatory role in lipid metabolism has made it a key focus in studies related to metabolic syndrome and obesity-related diseases. Quantitative analysis of 17α-estradiol allows researchers to better understand its dynamic changes in different pathological conditions, providing critical data for early disease diagnosis, treatment efficacy assessment, and personalized medicine. With its high sensitivity and precision, mass spectrometry is capable of accurately measuring 17α-estradiol levels in blood or urine, offering strong support for research in these fields.

       

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      Figure 1. The Structure of 17α-Estradiol

       

      MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomicsproteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of 17α-estradiol. We ensure the accuracy of the quantification of 17α-estradiol and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you are interested in our 17α-estradiol analysis service, please feel free to contact us at any time, and we will be fully committed to providing you with high-quality analytical services and technical support.

       

      Analysis Workflow

       

      1840293420649271296-Workflowof17α-EstradiolAnalysisService.PNG

       

      Service Advantages

      1. Advance Analysis Platform: MtoZ Biolabs established an advanced 17α-estradiol analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

       

      2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

       

      3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all 17α-estradiol analysis data, delivering clients a detailed and comprehensive data report.

       

      4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.

       

      Applications

      The analysis of 17a-estradiol is crucial in the following areas:

      • Understanding of hormone-related disorders
      • Discovery of new disease biomarkers
      • Enhancing disease diagnostics
      • Accelerating the development of innovative therapeutics
      • Unveiling novel insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      We accept serum, plasma, urine, tissues, and other biological samples. A minimum of three samples under the same condition should be provided for each type.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

       

      Samples must be stored at -80°C to maintain stability. Details on sample collection and handling should also be provided.

       

      Deliverables

      1. Comprehensive Experimental Details (Materials, Instruments and Methods,etc.

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 17α-Estradiol Analysis

      4. Raw Data

      5. Custom Analysis Report

       

      Our 17α-estradiol analysis service aims to facilitate your research and product development endeavors by delivering accurate and trustworthy results.

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