11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic Acid Analysis Service
- Precise quantification of 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid levels in various samples
- Profiling of 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid metabolic pathway
- Analysis of 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid function in pathological processes
- Expertise: Our team of experts has extensive experience in metabolomics and mass spectrometry analysis, ensuring high-quality results and accurate interpretations.
- Advanced Technology: Our cutting-edge LC-MS/MS systems provide high sensitivity and specificity for 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid analysis.
- Comprehensive Service: From sample preparation to data analysis, we provide a one-stop solution for your 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid analysis needs.
- Biomarker discovery for inflammatory diseases, cancer, and neurodegenerative disorders
- Drug metabolism studies
- Mechanistic studies in disease pathogenesis
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid, also known as Prostaglandin J2 (PGJ2), is an endogenous metabolite of Prostaglandin D2 (PGD2). PGJ2 is a potent agonist of the PGD2 receptor (DP) and plays a significant role in a variety of cellular processes. One of its key functions is the stimulation of intracellular cyclic AMP (cAMP) production, which is crucial in regulating cell signaling pathways. Additionally, PGJ2 has been shown to induce oxidative stress and promote apoptosis in neuronal cells, making it a critical molecule in the study of neurodegenerative diseases.
Research has demonstrated that PGJ2 induces the accumulation and aggregation of ubiquitinated (Ub) proteins, a hallmark associated with several neurodegenerative disorders. This includes conditions like Alzheimer's disease (AD) and Parkinson's disease (PD), where the accumulation of damaged proteins and oxidative stress contribute to the pathology. Given its neurotoxicity, PGJ2 is a key focus in understanding the molecular mechanisms underlying neurodegenerative diseases and developing potential therapeutic strategies.
Figure 1. The Structure of 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic Acid
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.
At MtoZ Biolabs, we offer a comprehensive 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid analysis service, which includes:
Analysis Workflow
Service Advantages
Applications
Our 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid analysis service is applicable in various fields, including:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic Acid
4. Raw Data
5. Custom Analysis Report
Please contact us for detailed information on our 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic Acid Analysis Service. We look forward to assisting you in your research endeavors.
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