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    11-Deoxycortisol Analysis Service

      11-Deoxycortisol is a steroid hormone produced by the adrenal gland, serving as a crucial intermediate in the cortisol synthesis pathway. As a precursor to glucocorticoids, 11-deoxycortisol is converted into cortisol in the body through the action of 11β-hydroxysteroid dehydrogenase, which is essential for metabolism, immune regulation, and stress response. Measuring 11-deoxycortisol levels is clinically significant for assessing adrenal function, diagnosing congenital adrenal hyperplasia (CAH), and monitoring the efficacy of related treatments.

       1826554694609784832-MolecularStructureof11-Deoxycortisol.png

      Figure 1. Molecular Structure of 11-Deoxycortisol

       

      MtoZ Biolabs offers 11-Deoxycortisol Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in 11-deoxycortisol detection.

       

      Analysis Workflow

       

      1826554767968161792-TheWorkflowof11-DeoxycortisolAnalysis.png

       

      Service Advantages

      1. High Sensitivity

      Detects very low concentrations of 11-deoxycortisol accurately.

       

      2. High Specificity

      Differentiates 11-deoxycortisol from other compounds using mass spectrometry.

       

      3. Rapid Analysis

      Efficient sample preparation and fast detection processes for high-throughput analysis.

       

      4. High Accuracy

      Strict quality control ensures accuracy and reproducibility.

       

      5. Versatility

      Capable of analyzing 11-deoxycortisol and its related metabolites.

       

      Sample Submission Requirements

      Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

       

      Applications

      • Essential for assessing adrenal function and diagnosing conditions such as CAH and other endocrine disorders.
      • Supports studies on the role of 11-deoxycortisol in glucocorticoid synthesis.
      • Facilitates research into the metabolism and pharmacodynamics of drugs related to 11-deoxycortisol.
      • Crucial for monitoring the efficacy of related treatments, guiding clinical interventions.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 11-Deoxycortisol

      4. Raw Data

      5. Custom Analysis Report

       

      Our 11-Deoxycortisol Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.

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