1-methylinosine Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art mass spectrometry platforms.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Basic biological research
- Drug discovery
- Biomarker identification
- Clinical diagnostics
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
1-Methylinosine (m1I) is a modified nucleoside derived from inosine, featuring a methyl group attached to the nitrogen atom at the first position of the purine ring. 1-Methylinosine is often found in anticodon of eukaryotic tRNA, where it plays a crucial role in maintaining the proper function and stability of the translational machinery. The methylation of inosine is catalyzed by specific methyltransferases, and this modification can impact codon recognition, translation efficiency, and overall protein synthesis.
Research on 1-methylinosine has gained momentum due to its involvement in post-transcriptional regulation and its potential role in disease mechanisms. Alterations in RNA modifications, including methylation patterns, have been linked to various disorders, including cancer, metabolic diseases, and neurodegenerative conditions. By studying the presence and dynamics of 1-methylinosine, researchers can gain deeper insights into RNA modifications and their biological implications, which can ultimately lead to the discovery of new therapeutic targets.
Figure 1. The Structure of 1-methylinosine
MtoZ Biolabs offers a comprehensive 1-methylinosine analysis service, utilizing cutting-edge mass spectrometry technologies to provide accurate and reliable data for researchers investigating this key RNA modification.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Comprehensive Information on 1-methylinosine
4. Raw Data
5. Custom Analysis Report
If you have any questions, please do not hesitate to contact us. Our team at MtoZ Biolabs is committed to providing you with the highest quality 1-Methylinosine analysis service.
How to order?
