1-methylguanosine Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art HPLC-MS platforms.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Biomarker Discovery: Identification of 1-methylguanosine as potential biomarkers in diagnostic or therapeutic applications.
- Drug Development: Understanding the role of 1-methylguanosine in diseases can aid in drug target discovery and validation.
- Disease Research: Our service can assist in studying the role of 1-methylguanosine in various diseases.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
1-methylguanosine (m1G) is a modified nucleoside found mainly in tRNA and rRNA, derived from the methylation of guanosine at the N1 position. It plays a fundamental role in the stability and functionality of these RNAs, mediating protein synthesis and therefore influencing various important biological processes, such as cellular metabolism, aging, and disease development. The abnormal metabolism of 1-methylguanosine has been associated with various pathological conditions, including cancer, making it an important target for biomarker discovery and therapeutic intervention. Understanding the roles of 1-methylguanosine and its metabolic pathways can provide significant insights into molecular mechanisms of disease and health. The detection and quantification of 1-methylguanosine can be used as a potential diagnostic tool or therapeutic target for diseases where its levels are aberrantly regulated.
Figure 1. The Structure of 1-methylguanosine
At MtoZ Biolabs, we use state-of-the-art technology, including high-resolution mass spectrometry, to offer accurate and comprehensive 1-methylguanosine analysis. Our service supports the identification and quantification of m1G modifications within RNA molecules, provides insights into its metabolic pathways, and investigates its potential links to disease. In addition, we provide a detailed report that includes the complete procedure, data interpretation, and an in-depth discussion of the biological and clinical significance of the findings.
Analysis Workflow
Service Advantages
Applications
Our 1-methylguanosine analysis service can be applied in various fields including but not limited to:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 1-methylguanosine
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing high-quality metabolomics services to accelerate your research. Contact us today and let our expert team assist you in your 1-methylguanosine analysis needs.
How to order?
