1,5-Anhydro-D-Glucitol Analysis Service
- Identifying novel disease biomarkers
- Boosting disease diagnosis capabilities
- Accelerating the discovery of innovative treatment modalities
- Gaining fresh insights into disease pathogenesis
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
1,5-Anhydro-D-glucitol (1,5-AG) is a sugar alcohol with the chemical formula C₆H₁₂O₅. Its structure consists of a six-carbon chain, similar to glucose, but lacks the hydroxyl group at the 1st and 5th carbon atoms. This compound is typically derived from the metabolism of certain sugars in plants and can also be found in various food sources, including fruits and vegetables. In biological systems, 1,5-AG plays a significant role as a marker for monitoring glycemic control. Its levels can reflect short-term fluctuations in blood glucose levels, making it useful for assessing diabetic conditions. 1,5-AG is primarily eliminated from the body through the kidneys, and its concentration in urine can provide insights into the body's glycemic status. 1,5-Anhydro-D-glucitol exhibits various biological activities, including influencing osmotic balance and cellular signaling. It can help protect cells from osmotic stress and may also participate in energy metabolism. The levels of 1,5-AG can be affected by dietary intake and metabolic conditions, and variations in its concentration may indicate alterations in glucose metabolism and insulin sensitivity, making it a potential biomarker for diabetes and other metabolic disorders.
Figure 1. The Structure of 1,5-Anhydro-D-Glucitol
Mass spectrometry-based metabolomics methods can simultaneously detect and quantify thousands of metabolic features and are widely used for the metabolic analysis of various compounds. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of 1,5-anhydro-D-glucitol. We ensure the accuracy of the quantification of 1,5-anhydro-D-glucitol and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you would like to learn more about our 1,5-anhydro-D-glucitol analysis services, please feel free to contact us, and we will be more than happy to assist you.
Analysis Workflow
Service Advantages
1. Experienced: MtoZ Biolabs has a professional research team and advanced technical equipment, capable of providing high-quality services and support to meet the specific needs of clients.
2. Wide Applicability: It is suitable for various types of samples, including plants, animals, and biological fluids, making it applicable across a broad range of fields.
3. High Throughput: Mass spectrometry technology can analyze multiple metabolites simultaneously in a short time, making it suitable for high-throughput analysis of large-scale samples.
4. Targeted Compounds: Targeted metabolomics focuses on specific metabolites, effectively eliminating interference signals and enhancing the reliability of the data.
5. Strong Detection Capability: Mass spectrometry technology can detect low concentrations of metabolites, making it suitable for analyzing rare or complex components in biological samples.
Applications
1,5-Anhydro-D-glucitol, a naturally occurring monosaccharide, has shown potential as a reliable biomarker for glycemic control, offering significant applications in:
Sample Submission Requirements
1. Sample Types
We accept diverse biological samples such as serum, plasma, urine, and tissues. For each sample, at least 3 replicates under the same condition are required.
2. Sample Volume
3. Sample Preservation
Samples should be stored at -80°C to maintain sample stability.
Note: Please provide detailed information about sample collection and handling procedures.
Deliverables
1. Experimental Procedures
2. Pertinent Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 1,5-Anhydro-D-Glucitol
4. Raw Data
5. Custom Analysis Report
With our 1,5-Anhydro-D-Glucitol Analysis Service, we aim to aid your research endeavors and product development initiatives by delivering reliable and precise results.
How to order?
