Taurochenodeoxycholic Acid Analysis Service

Taurochenodeoxycholic acid (TCDCA) is a bile acid synthesized in the liver through the conjugation of chenodeoxycholic acid (CDCA) with taurine, found in most species, including humans. After its secretion into bile, TCDCA is released into the intestine, where it typically remains ionized at physiological pH, though it can also crystallize as a sodium salt. In the small intestine, TCDCA acts as a detergent, facilitating the emulsification and absorption of fats by promoting lipid solubilization. It is then actively absorbed in the terminal ileum. As a medication, TCDCA serves as a choleretic, enhancing bile secretion from the liver, and as a cholagogue, aiding bile flow into the duodenum. Additionally, TCDCA is being explored for its potential in treating inflammation and cancer. These features make TCDCA particularly valuable in studies of bile acid metabolism, liver health, gut microbiota dynamics, and drug development.

 

Figure 1. Molecular Structure of Taurochenodeoxycholic Acid

 

MtoZ Biolabs offers Taurochenodeoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in TCDCA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of TCDCA accurately.

 

2. High Specificity

Differentiates TCDCA from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing TCDCA and its related metabolites.

 

Sample Submission Requirements

 



For detailed sample submission instructions, please consult our technical team.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Taurochenodeoxycholic Acid

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into TCDCA's extensive physiological roles through top-tier analytical techniques and expert services.