Sphingosine-1-Phosphate Analysis Service

Sphingosine-1-Phosphate (S1P) is a signaling sphingosine, which is the product of the phosphorylation of sphingosine by sphingosine kinase. S1P is dephosphorylated by sphingosine phosphatase to form sphingosine, and can be irreversibly degraded by sphingosine phosphate lyase. Many cells can secrete S1P, which then affects other cells in an autocrine or paracrine manner.

 

S1P has a wide range of biological functions. It has been proven to enhance cell growth and inhibit normal cell apoptosis. A lot of research indicates that S1P can promote tumor growth, anti-apoptosis, promote tumor angiogenesis and metastasis. By promoting the release of calcium from internal stores, S1P increases the calcium content within cells. In addition, S1P can also regulate pro-inflammatory cytokines, Toll-like receptor signal transduction and induce inflammation, which are associated with diabetes, obesity, and metabolic syndrome.

 

MtoZ Biolabs employs robust, reproducible, and sensitive systems for the separation, characterization, identification, and quantification of S1P, ensuring reliable, rapid, and cost-efficient analyses. Free project evaluation!