Serotonin Analysis Service

    Serotonin (5-hydroxytryptamine, 5-HT) is a crucial neurotransmitter and signaling molecule with wide-ranging effects in both the central nervous system and peripheral tissues. It is primarily found in the brain, gastrointestinal tract, and blood platelets, where it plays a vital role in regulating mood, cognition, sleep, appetite, and various other physiological functions.

     

    In addition to its role as a neurotransmitter, serotonin also functions in the regulation of cardiovascular health, gastrointestinal motility, and immune responses. Dysregulation of serotonin levels is associated with numerous disorders, including depression, anxiety, schizophrenia, and irritable bowel syndrome (IBS). Research into serotonin metabolism is therefore crucial for understanding these conditions and developing targeted therapeutic interventions.

     

    1831590428743946240-MultifacetedRegulationofMetabolismbyPeripheralSerotonin.png

     

    El-Merahbi, R. et al. FEBS Lett.. 2015.

     

    Figure 1. Multifaceted Regulation of Metabolism by Peripheral Serotonin

     

    At MtoZ Biolabs, we are equipped with advanced LC-MS/MS systems, capable of offering comprehensive serotonin analysis for your research. We can assist you to elucidate the metabolic pathways of serotonin, identify potential markers for disease diagnosis, and evaluate the efficacy of new therapeutics.

     

    Analysis Workflow

    1. Sample Preparation: We accept a variety of sample types, including body fluids, tissues, and cells.

    2. Extraction: Extraction of serotonin using a specialized protocol.

    3. Analysis: Utilizing LC-MS/MS for precise and accurate detection and quantification of serotonin.

    4. Data Analysis: Comprehensive data analysis including metabolic pathway analysis.

    5. Report: Detailed report with results and interpretation.

     

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    Service Advantages

    • Highly Efficient Sample Recovery and Processing
    • Accurate and Reliable Detection and Quantification
    • Capability to Handle Various Sample Types
    • Customized Data Analysis Services
    • Rapid Service Response and Cost-Effectiveness

     

    Applications

    Our serotonin analysis service can be applied in:

    • Neurotransmitter research
    • Disease biomarker discovery
    • Drug efficacy evaluation

     

    Sample Submission Requirements

     

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    • Samples should be stored at -80℃ and shipped with dry ice.
    • We recommend providing at least 3 samples of similar conditions for each type of sample.
    • Please provide details on sample collection and handling.
    • Other sample types, please contact us for more details.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Serotonin

    4. Raw Data

    5. Custom Analysis Report

     

    Contact us today to learn more about our serotonin analysis service and how we can assist in advancing your research.

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