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    Serine Analysis Service

      Serine is a crucial non-essential amino acid involved in various metabolic processes. It plays essential roles in protein synthesis, phospholipid metabolism, one-carbon metabolism, and neurotransmitter synthesis. Serine is a precursor for phosphatidylserine and sphingolipids, vital for maintaining cell membrane structure and function. It is also involved in the biosynthesis of methionine and cysteine and is critical in DNA synthesis and repair through the one-carbon metabolism pathway. In the nervous system, serine acts as a neurotransmitter and neuromodulator, influencing memory and cognitive functions. Additionally, serine plays a significant role in gluconeogenesis and creatine metabolism. Given its central role in these processes, precise analysis of serine and its metabolic pathways is essential for understanding its physiological functions and supports clinical research, disease diagnosis, and nutritional assessment.

       

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      Figure 1. Molecular Structure of Serine

       

      MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of serine and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of serine in complex biological matrices.

       

      Analysis Workflow

       

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      Experimental Instruments

      • Liquid Chromatography-Mass Spectrometry (LC-MS)
      • Gas Chromatography-Mass Spectrometry (GC-MS)
      • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

       

      Service Advantages

       

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      Applications

      Clinical Research: Monitor serine levels to study its role in metabolic diseases (such as diabetes and fatty liver disease) and other health conditions, aiding diagnosis and treatment.

       

      Nutritional Assessment: Analyze serine content in foods and supplements to evaluate nutritional value and guide dietary intake and supplementation strategies.

       

      Neuroscience Research: Assess the role of serine in neurotransmitter synthesis and study its potential applications in neurological diseases.

       

      Drug Development: Explore the potential applications of serine in new drug development, particularly for treating metabolic and neurodegenerative diseases.

       

      MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into serine's extensive physiological roles through top-tier analytical techniques and expert services.

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