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    Sebum Metabolomics Service

      Sebum, one of the main components of human skin, is secreted by sebaceous glands and mainly functions to protect and moisturize the skin. However, excessive sebum or changes in its composition can lead to various skin diseases such as acne, rosacea, and seborrheic dermatitis. Therefore, studying the metabolic changes of sebum is of great importance for understanding the pathogenesis and treatment of these skin diseases. MtoZ Biolabs provides sebum metabolomics services to help you explore the relationship between sebum metabolism changes and skin diseases.


      Services at MtoZ Biolabs

      MtoZ Biolabs provides advanced sebum metabolomics services, uncovering specific molecular markers linked to complex skin conditions. These insights support personalized treatment and skincare regimens. By deeply analyzing the metabolomic composition of sebum and utilizing cutting-edge platforms, we offer comprehensive metabolite analysis to foster scientific advancements in dermatology. As a strategic partner, MtoZ Biolabs is dedicated to unraveling the molecular intricacies of skin physiology.

      Our services include:

      1. Targeted Metabolite Analysis

      • Quantitative analysis of key sebum components such as lipids, fatty acids, and cholesterol.
      • Utilizes advanced mass spectrometry technology to ensure precise measurements.

      2. Non-Targeted Metabolomics

      • Comprehensive analysis of a wide range of metabolites in sebum samples.
      • Identifies metabolic patterns associated with various skin states and external factors.

      3. Isotope Tracing Studies

      • Uses stable isotope labeling to study the metabolic pathways of the skin.
      • Analyzes isotopic enrichment in metabolites to deeply explore sebum composition and lipid metabolism.

      4. Metabolic Pathway Analysis

      • Creates sebum metabolic pathway diagrams to identify key metabolic intermediates and regulatory factors.
      • Integrates data analysis to fully interpret the metabolic networks within the skin.

      5. Data Analysis and Interpretation

      • Employs professional techniques to process and analyze metabolomics data.
      • Identifies significant metabolic changes and adjustments in metabolic pathways, generating comprehensive research reports.




      Experimental Instruments

      1. LC-MS (Liquid Chromatography-Mass Spectrometry)

      • Integrates advanced liquid chromatography with mass spectrometry to precisely analyze both polar and non-polar metabolites in sebum.

      2. GC-MS (Gas Chromatography-Mass Spectrometry)

      • Provides detailed measurements of volatile and semi-volatile metabolites using high-precision equipment.


      Sample Submission Requirements

      • Whole Sebum Samples: Includes lipids, proteins, and metabolites for a comprehensive understanding of skin health.
      • Surface Lipid Extracts: Detailed analysis of the lipidomic features.
      • Sample Collection and Preservation: Collection tools must be kept clean to avoid contamination. Samples should be stored in sterile containers and kept as cool as possible to maintain metabolite stability.


      MtoZ Biolabs is a mature partner in biopharmaceutical research, with rich experience in sebum metabolomics analysis. We provide skin disease solutions oriented towards sebum metabolomics analysis to accelerate the exploration of new scientific horizons. If you want to know more information, please contact us. We look forward to cooperating with you.

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