Resources

Proteomics Databases



Metabolomics Databases

• • Mass Spec Sequencing

  Mass spec sequencing is a method used to determine the sequences of biological macromolecules, such as proteins and nucleic acids, by measuring their molecular mass. This technique enhances our understanding of biomolecular functions. The core principle involves ionizing the sample before analysis with a mass spectrometer, where ions are examined based on their mass-to-charge ratio (m/z). In proteomics, mass spec sequencing facilitates the identification of protein amino acid sequences, which aids in ......

• • Mascot Protein Identification

  Mascot protein identification is a widely used bioinformatics method in the field of proteomics, combining mass spectrometry technology with database searches to identify proteins by analyzing the mass data of peptides. As a commercial software tool, Mascot plays a crucial role in proteomics research, enabling researchers to quickly and accurately identify proteins within complex biological samples. In proteomics research, protein identification is a key step in elucidating the protein composition of ......

• • How to Determine Protein Molecular Weight Effectively?

  How to determine protein molecular weight effectively? Protein molecular weight determination not only helps to define the basic physicochemical properties of proteins but also plays a key role in verifying protein structure, assessing sample purity, and studying protein complex assembly states. In fields such as biopharmaceuticals, protein engineering, genetic engineering, and disease research, precise protein molecular weight determination is crucial for both scientific research and industrial appli......

• • LC-ESI-MS/MS Proteomics

  LC-ESI-MS/MS proteomics is extensively employed to investigate the protein composition, structure, and function in biological samples. This technique integrates the benefits of liquid chromatography and mass spectrometry, facilitating the efficient separation, detection, and identification of diverse proteins. Liquid chromatography effectively separates mixture components, enhancing the precision of subsequent mass spectrometric analysis. Electrospray ionization, a method for ionizing proteins for mas......

• • Proteomics Research: Tools, Challenges, and Future Directions

  Proteomics research is a vital area within modern life sciences, dedicated to understanding the protein composition and functions in biological systems. With the advances made in genomics, proteomics has emerged as a pivotal field for comprehending life processes, disease mechanisms, and drug development. The progress in proteomics research relies heavily on a range of cutting-edge technologies, including high-resolution mass spectrometry, liquid chromatography, and bioinformatics, though it is also c......

• • Proteomics Analysis: Methods, Applications, and Limitations

  Proteomics Analysis is a critical methodology in life sciences, focused on studying the composition, structure, function, and interactions of all proteins within cells, tissues, or organisms. Unlike genomics, proteomics not only helps us understand the final products of gene expression but also reveals the post-translational modifications, dynamic changes, and regulatory mechanisms of proteins. Therefore, it finds broad applications in disease research, drug discovery, precision medicine, and agricult......

• • Proteomics Mass Spectrometry Analysis: Principles and Key Applications

  Proteomics mass spectrometry analysis is a fundamental technique in modern life sciences for studying protein composition, structure, and function. By utilizing highly sensitive mass spectrometry platforms for protein detection and quantification, this approach enables researchers to investigate dynamic changes in protein expression, post-translational modifications, and protein interactions in biological processes. Recent advancements in mass spectrometry technology have enhanced the precision and th......

• • Proteomics Analysis: Methods, Technologies, and Applications

  Proteomics analysis is a scientific approach to reveal life processes by systematically studying the composition, function, and roles of proteins within cells. Unlike genomics, proteomics focuses not only on gene expression products but also on how these products contribute to biological systems through post-translational modifications, interactions, and their dynamic changes. With continuous advancements in high-throughput technologies and sophisticated analytical techniques, proteomics has become a ......

• • Protein Identification and Quantification: Techniques and Strategies

  Proteins are essential to biological systems, with their structure, abundance, and dynamic changes being critical to the regulation of normal biological processes and the onset of disease. Consequently, protein identification and quantification are fundamental to fields such as basic research, disease diagnostics, and drug development. With the rapid advancement of mass spectrometry technologies and high-throughput proteomics methods in recent years, researchers can now analyze protein types and abund......

• • Peptide LC-MS/MS

  Peptide LC-MS/MS analysis is a highly efficient method that integrates liquid chromatography (LC) and mass spectrometry (MS) techniques, predominantly utilized in proteomics research. This technique involves digesting proteins from complex biological samples into smaller peptides, which are then separated using liquid chromatography. The separated peptides undergo mass spectrometric analysis to determine their mass, allowing for both qualitative and quantitative protein assessments. A primary advantag......