Resources

Proteomics Databases



Metabolomics Databases

• • Tissue Proteomics

  Tissue proteomics is the study of protein types, structures, modifications, and biological functions across different tissues. Unlike single-cell or fluid proteomics, this approach preserves cellular microenvironments and spatial information, revealing protein expression changes and interactions. Since tissues are complex systems composed of diverse cells, protein dynamics are influenced by genetics, metabolism, and disease states. Tissue proteomics is widely used in disease mechanism research, biomarker...

• • Specific Protein Quantification

  Specific protein quantification is a technique used to precisely measure the concentration of target proteins in complex biological samples. This process involves multiple methods and technologies, with mass spectrometry (MS) being one of the most widely used techniques. MS is commonly applied in proteomics research, biomarker discovery, and drug mechanism studies. Enzyme-linked immunosorbent assay (ELISA) is another method for specific protein quantification. ELISA utilizes high-affinity antibody binding..

• • Tandem Mass Spectrometry Proteomics

  Tandem mass spectrometry proteomics is a powerful technique that enables the comprehensive analysis of proteins within biological systems. This method focuses on separating, identifying, and quantifying complex protein mixtures to gain deeper insights into protein structures, functions, and their roles in biological processes. The applications of tandem MS proteomics are extensive, including but not limited to the discovery of disease biomarkers, identification of drug targets, analysis of cellular.........

• • Glycoprotein Enrichment

  Glycoprotein enrichment refers to the selective extraction and concentration of glycosylated proteins from complex biological samples using specialized techniques. Glycoproteins are proteins that contain covalently attached glycan structures and are fundamental components of various biological systems, including cell membranes, secreted proteins, and serum proteins. As a major post-translational modification, glycosylation significantly influences protein function, stability, localization, and interactions.

• • SILAC-Based Proteomics

  SILAC-based proteomics is a powerful and precise technique used to study protein expression and modifications in cell biology and molecular biology. SILAC, or Stable Isotope Labeling by Amino Acids in Cell Culture, is a method that enables quantitative protein analysis by incorporating stable isotope-labeled amino acids into cells during culture. The core principle of SILAC-based proteomics is the replacement of natural amino acids with stable isotope-labeled ones (e.g., ¹³C or ¹⁵N-labeled lysine and.......

• • Lipidome Analysis

  Lipidome analysis technology is a technique specifically designed to study the composition of lipid molecules in organisms, their metabolic pathways, and the roles of lipids in physiological and pathological states. Lipids are the main components of cell membranes and are also key molecules in energy storage and signal transduction. Lipidomics systematically analyzes lipid molecules in cells, tissues, or body fluids to reveal their multiple roles in biological processes. The application of lipidome ........

• • Hydroxyproline Analysis

  Hydroxyproline analysis is a specialized technique for quantifying hydroxyproline in biological samples and investigating its role in various biological processes. Hydroxyproline is a hydroxylated amino acid that plays a pivotal role in collagen biosynthesis. As the most abundant structural protein in the human body, collagen is extensively distributed in tissues such as skin, bone, and blood vessels, where it is essential for maintaining structural integrity and cellular function. Given that hydroxypr.....

• • Soil Proteomics

  Soil proteomics is an advanced interdisciplinary field that investigates the composition, structure, and function of proteins in soil environments. As a convergence of proteomics and soil science, this research area primarily explores the dynamic changes in soil microbial proteins and plant rhizosphere-secreted proteins, aiming to elucidate the molecular mechanisms underlying soil nutrient cycling, microbial ecological functions, and environmental pollution remediation. Soil, as one of the most complex.....

• • SILAC Quantification

  SILAC quantification is a widely used quantitative technique in proteomics research that enables precise measurement of protein abundance changes across different samples by incorporating stable isotope-labeled amino acids during cell culture. This method is particularly well-suited for comparative protein quantification in biological experiments, offering high accuracy and sensitivity, especially when analyzing protein expression differences under varying conditions or treatment groups. The fundamental....

• • Proteomics in Agriculture

  Proteomics in Agriculture is an emerging field that investigates the composition, structure, function, and regulatory mechanisms of proteins in agricultural organisms. As a specialized branch of proteomics, Proteomics in Agriculture primarily focuses on crops, livestock, aquaculture species, and agricultural microorganisms. By analyzing protein expression and regulatory patterns, researchers aim to uncover the molecular mechanisms governing biological processes such as growth and development, disease.......