Resources

Proteomics Databases



Metabolomics Databases

• • Recombinant Protein Vaccine DLS (Dynamic Light Scattering) Analysis

  Recombinant protein vaccines are a type of vaccine that do not contain a complete pathogen and are prepared from specific protein antigens produced by a heterologous expression system. Due to their high safety, stability, and relatively low cost, recombinant protein vaccines have gained widespread attention from researchers in recent years.

• • HPLC Peptide Mapping Analysis of Recombinant Protein Drugs

  Recombinant protein drugs are produced by biotechnological means, especially gene recombination technology. These drugs have high specificity and activity, and can produce precise pharmacological effects on target molecules. Since they are prepared based on biological processes, their purity, stability, and structural integrity are key quality attributes. Accurate and reliable analysis and quality control of these drugs is crucial to ensure their safety and efficacy.

• • Detection of Proteomic Changes Using SILAC/Dimethyl Labeling

  In contemporary biological research, proteomics stands at the forefront of elucidating the functions and mechanisms of biological systems. Protein expression levels, post-translational modifications, and interactions are pivotal in cellular biology studies. Within proteomics, quantitative analysis serves as a vital approach to uncovering these molecular shifts.

• • DIA-Based Detection and Analysis of Protein Biomarkers

  In modern biomedical research, the detection and analysis of protein biomarkers are critical for diagnosis, treatment, and disease monitoring. Data-Independent Acquisition (DIA), an advanced mass spectrometry technique, is widely used in proteomics due to its high throughput, reproducibility, and broad data coverage.

• • Phosphoproteomics Analysis Based on TMT Labeling

  Phosphorylation is a crucial post-translational modification (PTM) that plays an essential role in controlling protein function, cellular signaling, and metabolic processes. Aberrant phosphorylation is often closely linked to the development and progression of various diseases. Therefore, comprehensive phosphoproteomic analysis is vital for understanding biological processes and disease mechanisms.

• • Quantitative Analysis of Protein Binding Affinity Using Far-Western Blot

  Protein-protein interactions (PPIs) are essential to biological processes such as cellular signaling, metabolic regulation, and immune responses. Quantitative analysis of protein binding affinity is critical for understanding these interactions' biological significance. Far-Western blotting, a specialized protein analysis technique, employs labeled probe proteins to detect interactions with target proteins, enabling the precise quantification of binding affinity.

• • Analysis of Protein Complexes Using AP-MS

  Protein complexes play essential roles in various cellular functions, including signal transduction, metabolic regulation, and gene expression. Understanding the composition and interactions of these complexes is crucial for unraveling cellular functions and elucidating disease mechanisms. In recent years, Affinity Purification-Mass Spectrometry (AP-MS) has emerged as a powerful technique widely used in protein complex research.

• • Analysis of Protein Complexes Using Co-Immunoprecipitation and Mass Spectrometry

  Proteins typically function within cells as part of complexes, and the assembly and dynamic changes of these complexes are crucial for understanding cellular signaling, metabolic pathways, and other biological processes. The combination of immunoprecipitation (Co-IP) with mass spectrometry (MS) is a powerful technique for studying and dissecting the composition and interaction networks of protein complexes.

• • Application of PCT-DIA Proteomics

  Proteomics is an essential tool in modern life sciences for studying protein expression, function, and interactions. Among the various proteomics techniques, Data-Independent Acquisition (DIA) based methods have become increasingly popular due to their high throughput, sensitivity, and quantitative accuracy. However, as proteomics research advances, there is a growing demand for efficiency and consistency in protein sample preparation.

• • Mechanism of PCT-DIA Proteomics

  Proteomics, the field dedicated to the study of the structure, function, and interactions of proteins within a biological system, is fundamental to advancing our understanding of life sciences. The integration of Pressure Cycling Technology (PCT) with Data-Independent Acquisition (DIA) represents a significant advancement in proteomics, enhancing both the efficiency and precision of analysis.