Resources
Proteomics Databases
Metabolomics Databases
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• Principle of O-Glycosylation Site Analysis in Biological Products
O-glycosylation is a significant post-translational modification involving the addition of sugar molecules to serine or threonine residues, crucial for biological functions such as protein stability, functionality, and intercellular interactions. This analysis has become a key focus in understanding protein functions and disease mechanisms in modern biotechnology.
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• Personalized Cancer Treatment: Immuno-Peptidomics and MS Reveal the Secrets of Tumor Neoantigens
Immunopeptidomics research focuses on exploring all peptides related to the antigen presentation process. These peptides play a crucial role in both cell-mediated and humoral immune responses. Immunopeptidome refers to the study of the complete set of peptides presented by MHC class I or II molecules on nucleated cells involved in antigen presentation pathways. They are essential for investigating immunogenic epitopes involved in cell-mediated and humoral immune responses.
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• X-Ray Powder Diffraction Analysis of Peptide Drug
Peptide drugs are biologically active molecules composed of multiple amino acids linked by peptide bonds. Typically, they consist of 10 to 100 amino acids with a relative molecular weight below 10,000. Most peptide drugs originate from endogenous or natural peptides, thus they have little to no side effects on the human body. Compared to protein drugs, peptide drugs also offer advantages such as good stability, high purity, low production costs, and low immunogenicity.
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• Inactivated Vaccine Viral Inactivant Residue Testing
Inactivated vaccines are vaccines that are made by culturing and then inactivating the pathogenic microorganisms. They are a common type of vaccine. By culturing and inactivating bacteria, viruses, or rickettsiae, the vaccines lose their pathogenicity to target organs while preserving the immunogenicity of the antigens. They can stimulate the immune system to produce an immune response, thereby achieving the purpose of disease prevention and treatment.
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• Quantitative Analysis of Ubiquitinated Proteins Based on High-Resolution Mass Spectrometry
Ubiquitin is a small regulatory protein that plays a crucial role in various biological processes such as protein degradation, signal transduction, and DNA repair. Through ubiquitination, ubiquitin attaches to target proteins, marking them for degradation or regulating their function. Investigating ubiquitination mechanisms is critical for understanding protein metabolism, homeostasis, and related diseases.
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• Ubiquitinomics Analysis by Peptide Enrichment and LC-MS/MS
Ubiquitination is a crucial post-translational modification that regulates various cellular functions, including protein degradation, signal transduction, and DNA damage repair. Abnormal ubiquitination is often associated with the development of various diseases, such as cancer and neurodegenerative disorders. Therefore, studying ubiquitination and its mechanisms in cell biology is essential for understanding disease pathogenesis and identifying potential therapeutic targets.
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MtoZ Biolabs offers a detailed amino acid metabolic profiling service that provides in-depth insights into the status and function of amino acids within various biological systems. Our amino acid metabolic profile analysis focuses on identifying free amino acids, secondary metabolites, and their roles in processes such as photosynthesis, protein synthesis, and cell growth. We analyze key metabolites in pathways that contribute to enhancing plant growth, increasing metabolic stability, and optimizing photosy
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Amino acids and their derivatives play crucial roles in various biological functions, serving as the fundamental units of proteins and participating in critical metabolic pathways such as neurotransmission, immune response, and energy production. The precise quantification of amino acids and their related compounds in biological samples is essential for understanding their roles in health and disease. To meet the growing demand for high-precision metabolomics research, MtoZ Biolabs offers a specialized MRM-
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• MRM-Based Targeted Metabolomics: Absolute Quantitative Analysis of Bile Acids
Given the biological and clinical importance of bile acids, accurate and comprehensive quantification is crucial for understanding their physiological and pathological roles. MtoZ Biolabs provides a highly sensitive and precise service for the absolute quantitative analysis of bile acids based on Multiple Reaction Monitoring (MRM) technology coupled with liquid chromatography-mass spectrometry (LC-MS).
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MtoZ Biolabs is proud to offer a comprehensive Short-Chain Fatty Acid (SCFA) analysis service based on advanced GC-MS technology. SCFAs, such as acetate, propionate, butyrate, and others, are essential metabolites in various biological systems, particularly in the gut microbiome. Their roles in metabolism, immune regulation, and disease progression make them critical research targets for understanding microbial-host interactions, obesity, inflammation, and metabolic disorders.
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