Resources

Proteomics Databases



Metabolomics Databases

• • Absolute Quantification in Targeted Proteomics

  Targeted proteomics is one of the critical technological approaches in modern biological research, utilizing mass spectrometry (MS) to quantify specific proteins or protein groups. Unlike discovery-based studies in traditional proteomics, targeted proteomics focuses on the precise measurement of known proteins, enabling deeper insights into their biological functions and clinical applications.

• • Protein Interaction Analysis Using Bioinformatic Methods

  Proteins, as fundamental molecules of life, participate in nearly all processes within living organisms, executing functions and transmitting information. Protein-protein interactions (PPIs) are at the core of various biological processes such as signal transduction, metabolic regulation, and cell cycle control. Therefore, elucidating the interactions between proteins is critical for understanding biological functional networks, disease mechanisms, and drug target development.

• • PRM-Based Analysis of Targeted Proteomics

  Targeted proteomics is a critical approach for protein research, enabling the quantification of specific proteins or peptides. This technology plays a significant role in studying changes in protein expression and mechanisms within complex samples. Among various targeted proteomics methods, Parallel Reaction Monitoring (PRM) has gained attention due to its high sensitivity, specificity, and throughput.

• • Detection Steps in Cellular Proteomics Using Liquid Chromatography

  Proteomics is a crucial field that studies all proteins and their interactions within a cell, tissue, or organism. Liquid Chromatography (LC) combined with Mass Spectrometry (MS) is one of the core techniques in proteomics research, particularly suitable for the efficient separation and identification of proteins in complex samples.

• • Glycated Albumin Measurement and High-Performance Liquid Chromatography

  Glycated albumin is a type of biomarker that is of significant importance in the diagnosis and monitoring of diabetes and other chronic diseases. Its measurement is crucial for understanding disease progression and evaluating treatment effectiveness. In the field of biopharmaceuticals, high-performance liquid chromatography (HPLC) has become a commonly used and effective method for the determination of glycated albumin.

• • Deciphering the Mechanisms of Histone Modification

  Proteomics of post-translational modifications (PTMs) is a scientific field that studies the expression, structure, and function of proteins within organisms. In biology, protein modifications are crucial mechanisms for cellular regulation and signal transduction. PTM proteomics analysis is an emerging technique that reveals the important roles of protein modifications in cellular processes through high-throughput analysis of histone modifications.

• • Common Methods for Assessing Protein-Protein Interactions

  Protein-Protein interactions are crucial biological processes in which proteins interact with each other to perform various functions in organisms. These interactions play important roles in cell signaling, metabolism regulation, immune response, and other biological processes. Understanding protein-protein interactions is of great significance in the field of biopharmaceutical research and drug development.

• • IP-MS Revealing Interaction Mechanisms Between Viral and Host Proteins

  Virus infection has always been an important public health issue worldwide, posing a serious threat to human health and life safety. In recent years, revealing the interaction mechanisms between viruses and host cells has become an important research direction.

• • How to Optimize Mass Spectrometry for Revealing Protein Composition?

  Proteomics is an important field in biology that studies the function and interactions of proteins in cells and organisms. Mass spectrometry analysis, as one of the key technologies in proteomics research, plays an irreplaceable role in deciphering complex protein mixtures.

• • Methods for Determining Protein Purity

  Protein is an important biomolecule in organisms, and its purity directly affects the quality and efficacy of biopharmaceuticals. Therefore, accurate determination of protein purity is a crucial task in the field of proteomics in biopharmaceuticals. In purity determination, choosing the appropriate method is essential. This article will introduce several common determination methods.