Resources

Proteomics Databases



Metabolomics Databases

• • Peptide Fingerprinting

  Peptide fingerprinting is a powerful mass spectrometry-based technique for protein identification and analysis. This approach utilizes the mass and charge properties of peptides produced by enzymatic digestion of proteins. By generating a distinct "fingerprint" from the mass spectra of these peptides, researchers can accurately identify and characterize proteins. The method's reliance on the unique peptide profiles generated by specific enzymatic digestion, such as with trypsin, has made it a cornerst......

• • Protein Mass Fingerprinting

  Protein mass fingerprinting (PMF) is a mass spectrometry-based technique designed for protein analysis and identification. The fundamental principle involves measuring the masses of peptides generated through enzymatic digestion of proteins, thereby creating a unique "fingerprint" spectrum. This spectrum is then matched with reference data from established protein databases to determine the protein's identity. Renowned for its efficiency, precision, and rapidity, PMF has become a cornerstone methodolo......

• • How Does Mass Spectrometry Work for Proteins

  Mass spectrometry is a powerful technique widely used in protein analysis to separate and detect molecules based on their mass-to-charge ratio (m/z). In this process, sample molecules are ionized, and the resulting ions are accelerated or deflected by electric or magnetic fields. This allows for the separation of ions according to differences in their mass and charge. The intensity and m/z ratios of the ions are then recorded by a detector, generating a mass spectrum that provides detailed information......

• • MtoZ Biolabs' Precision Protein Lactylation Modification Analysis Service

  MtoZ Biolabs offers integrated protein lactylation modification analysis service, utilizing advanced Thermo Orbitrap Exploris™ 240 mass spectrometer and Nano-LC system. This service provides highly accurate identification of lactylation sites and in-depth analysis of their dynamic changes across diverse conditions. Tailored for functional proteomics, metabolic studies, and disease research, it delivers critical insights into the regulatory roles of lactylation, setting the stage for deeper exploration of...

• • DIA based Protein Quantitative Service at MtoZ Biolabs

  MtoZ Biolabs offers DIA based protein quantitative service, utilizing the advanced AB SCIEX Triple-TOF 5600+ high-resolution mass spectrometry system. This system combines high-speed scanning, enhanced quantitative sensitivity, and the advantages of quadrupole tandem mass spectrometry, integrating high resolution, precise mass stability, ultra-high sensitivity, and rapid scanning capabilities.

• • Comprehensive High-Resolution MS Molecular Weight Identification Service by MtoZ Biolabs

  MtoZ Biolabs, a prominent provider of high-resolution MS molecular weight identification service, has developed a comprehensive mass spectrometry platform that integrates matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and electrospray ionization mass spectrometry (ESI-MS) technologies. By utilizing state-of-the-art high-resolution mass spectrometry instruments and implementing optimized analytical protocols, MtoZ Biolabs delivers molecular weight identification..

• • TMT Quantitative Proteomics Analysis Service, Assisting Cutting-Edge Scientific Research

  MtoZ Biolabs offers TMT quantitative proteomics analysis service powered by the advanced Orbitrap Fusion Lumos mass spectrometer and Nano-LC system, ensuring high-resolution, high-sensitivity protein identification and quantification. This service employs a dual fragmentation strategy (HCD and ETD) to achieve comprehensive detection of low-abundance proteins while delivering reliable, high-quality data.

• • Can Mass Spectrometry Determine Protein Structure?

  In protein research, determining protein structure is critical for understanding its function, interactions, and role in diseases. As a powerful analytical tool, mass spectrometry has become an increasingly important method in protein studies. But can mass spectrometry determine protein structure?   Traditionally, X-ray crystallography and nuclear magnetic resonance (NMR) have been the primary techniques for determining protein structures. X-ray crystallography provides high-resolution three-dimension......

• • What are the Two Methods in Protein Identification by Mass Spectrometry?

  Protein identification is a critical component of proteomics, and mass spectrometry (MS) is one of the most essential techniques for this purpose. Below, two commonly used MS methods for protein identification are described:   Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) 1. Technical Principles In MALDI-TOF MS, protein samples are mixed with a matrix, and then subjected to laser irradiation. This process generates gas-phase ions from the sample and matrix......

• • Can Mass Spectrometry be Used for Protein Sequencing?

  Protein sequencing directly reveals the amino acid sequence of proteins, which is essential for understanding their structure and function. With the amino acid sequence determined, the three-dimensional structure of the protein can be predicted, which facilitates the understanding of its biological roles and interaction mechanisms. This is crucial for studying biological processes and disease mechanisms. Current protein sequencing technologies include de novo mass spectrometry sequencing, Edman degrad......