• Home
  • Biopharmaceutical Research Services
  • Multi-Omics Services
  • Support
  • /assets/images/icon/icon-email-2.png



    Protein Peptide Drug Mass Spectrometry Analysis

      In the field of modern drug research and development, mass spectrometry analysis of protein peptide drugs is a crucial step. This analysis not only helps to understand the molecular structure of drugs, but also ensures their safety and effectiveness. With the rapid development of biotechnology, protein peptide drugs have become an important means to treat various diseases, and mass spectrometry analysis provides the necessary information at the molecular level.


      Characteristics of Protein Peptide Drugs

      Protein peptide drugs are generally large molecule biologics composed of short-chain or long-chain amino acids. Compared with traditional small molecule drugs, they have higher targeting and biological activity, but are also more likely to be affected by environmental factors, such as temperature, pH, and enzyme action. Therefore, strict quality control and structural analysis of these drugs become particularly important.


      Principle of Mass Spectrometry Analysis

      Mass spectrometry analysis is a technique for measuring molecular mass. It ionizes the sample, generates charged molecules or molecular fragments, and separates them based on their mass-to-charge ratio (m/z). This process can accurately determine the mass of the molecule and reveal its chemical structure information.


      Analysis Workflow

      1. Sample Preparation

      The sample needs to be prepared through appropriate methods, which may include protein extraction, purification, and concentration.


      2. Ionization Technique

      The sample is ionized in the mass spectrometer. Common ionization methods include electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI).


      3. Mass Analysis

      The ionized molecules are separated inside the mass spectrometer, and the analyst can obtain the mass spectrum based on the difference in the mass-to-charge ratio.


      4. Data Processing

      Use professional software to process and interpret the spectrum, to determine the molecular weight, sequence, and any chemical modifications of proteins or peptides.



      Mass spectrometry analysis plays a key role in the development and production of protein peptide drugs. It is not only used in new drug development, but also in monitoring quality control during production, and in completing batch release testing of drugs.


      The mass spectrometry analysis of protein peptide drugs is a complex but indispensable process that ensures the quality and safety of the drugs. With the continuous advancement of technology and the development of new methods, mass spectrometry analysis will continue to play an irreplaceable role in drug research and development and the field of biotechnology.

    Submit Inquiry
    Name *
    Email Address *
    Phone Number
    Inquiry Project
    Project Description *


    How to order?


    Submit Inquiry