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    PCS Analysis Service

      The compounds related to free PCS mainly include p-cresol and its sulfate ester form, p-cresyl sulfate. p-Cresol is produced by gut microbiota metabolism and is subsequently converted into free PCS in the liver. These compounds exhibit significant biological activity in the human body, particularly in patients with chronic kidney disease, where free PCS is considered a uremic toxin closely associated with cardiovascular disease and kidney function deterioration. The metabolites of free PCS primarily include p-Cresol, which are involved in the interactions between gut microbiota and host metabolism, playing roles in various biological processes. Analyzing the levels of free PCS and its metabolites in plant and biological samples is crucial for understanding their role in gut health, kidney damage, and metabolic disorders. Additionally, studying the presence of these metabolites in plants can help explore their potential roles in plant metabolism and stress responses.

       

      Services at MtoZ Biolabs

      MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes an LC-MS-based metabolomics platform for the analysis of PCS. We ensure the accuracy of the quantification of PCS and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you are interested in our PCS analysis service, please feel free to contact us at any time, and we will be fully committed to providing you with high-quality analytical services and technical support.

       

      Analysis Workflow

       

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      Service Advantages

      1. Advance Analysis Platform: MtoZ Biolabs established an advanced PCS analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

       

      2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

       

      3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all PCS analysis data, delivering clients a detailed and comprehensive data report.

       

      4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.

       

      Applications

      • Discovering new disease biomarkers  
      • Enhancing disease diagnosis  
      • Speeding up the discovery of innovative therapeutics  
      • Uncovering new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Store at -80°C to maintain stability.

       

      Note: Provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on PCS

      4. Raw Data

      5. Custom Analysis Report

       

      Through our PCS analysis service, we aim to facilitate your research and product development processes by providing accurate and reliable results.

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