NAm Analysis Service
- Comprehensive: Our service covers the entire process from sample preparation to data analysis.
- Reliable: The LC-MS-based method ensures high accuracy and reproducibility.
- Flexible: We offer tailor-made solutions to meet specific needs of your research.
- Fast: Turnaround time is within weeks.
- Determination of NAm content in various biological samples.
- Pharmacokinetic studies of NAm.
- Metabolomic studies on the effect of NAm on disease models.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
NAm (Nicotinamide), with the chemical formula C₆H₆N₂O, is a form of vitamin B3. Its chemical structure includes a pyridine ring and an amine group, exhibiting hydrophilicity and biocompatibility. NAm is primarily sourced from foods such as meat, fish, nuts, and legumes, and can also be synthesized from the amino acid tryptophan in the body. In terms of biological activity, NAm plays a crucial role in cellular energy metabolism as a precursor to coenzymes NADH⁺ and NADP⁺, participating in redox reactions and DNA repair, and exhibiting anti-inflammatory and antioxidant properties. Additionally, its metabolites, such as nicotinic acid and N-methyl nicotinamide, also possess biological activity, regulating metabolism and immune responses. Analyzing the content of NAm and its metabolites in plants and biological samples holds significant importance. This not only helps assess the nutritional value and health impacts of foods but also reveals their roles in plant growth, stress resistance, and human health. Understanding the variations in these components aids in optimizing agricultural production, improving nutritional intake, and formulating public health policies.
Figure 1. The Structure of NAm
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Our NAm analysis service is based on liquid chromatography-mass spectrometry (LC-MS), a powerful tool for the identification and quantification of NAm in various biological samples. This service aims to facilitate your research on the bioactivity of NAm and its potential applications in pharmaceutical and nutraceutical industries.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample types
Serum, plasma, urine, tissues, and other biological samples.
2. Sample volume
3. Sample preservation
Store at -80°C to maintain stability.
Deliverables
1. Experimental procedures
2. LC-MS parameters
3. Detailed information on NAm
4. Raw data
5. Custom analysis report
Please feel free to contact us if you need our NAm Analysis Service. We are committed to providing you with high-quality analytical services and technical support.
How to order?
