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    N-methyladenosine Analysis Service

      N-Methyladenosine (m6A) is the most prevalent internal modification of mammalian mRNA and is critical for the regulation of RNA metabolism. It is an abundant modification in mRNA and is found in different types of RNA, including tRNA, rRNA, and others. m6A impacts various biological processes and plays a significant role in disease progression, especially in cancer and neurological disorders.

       

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      Figure 1. The Structure of N-methyladenosine

       

      The m6A modification has been linked to various biological processes, such as mRNA stability, translation efficiency, and alternative splicing. Hence, studying this critical RNA modification can provide insights into the underlying molecular mechanisms of various diseases. Furthermore, the analysis of m6A can also serve as a potential biomarker for disease diagnosis and treatment.

       

      MtoZ Biolabs utilizes advanced LC-MS/MS system for m6A analysis, offering a comprehensive m6A profiling service. We can help you quantify m6A in different RNA types across various conditions and species.

       

      Analysis Workflow

       

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      Service Advantages

      • One-stop solution: From sample preparation to data analysis.
      • Advanced technology: High-resolution LC-MS/MS platform.
      • Professional team: Expertise in m6A analysis and interpretation.
      • Comprehensive report: Detailed experimental procedures, bioinformatics and statistical analysis, results interpretation, and conclusions.

       

      Applications

      Our m6A analysis service can be applied to:

      • Study the role of m6A in various biological processes.
      • Investigate the function and mechanism of m6A in disease progression.
      • Identify potential biomarkers for disease diagnosis and treatment.

       

      Sample Submission Requirements

       

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      • Samples should be stored at -80℃ and shipped with dry ice.
      • We recommend providing at least 3 samples of similar conditions for each type of sample.
      • Please provide details on sample collection and handling.
      • Other sample types, please contact us for more details.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on N-methyladenosine

      4. Raw Data

      5. Custom Analysis Report

       

      For any further information about our N-methyladenosine Analysis service, please feel free to contact us at MtoZ Biolabs. We are dedicated to providing the most satisfactory service for you.

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