Molecular Size Variation Analysis Service

• • SEC Based Molecular Size Variation Analysis Service

  Molecular size variation critically influences the properties of biomacromolecules such as proteins, antibodies, and peptides, especially in the realms of drug research and bioproduct manufacturing. Size Exclusion Chromatography (SEC), also known as Gel Permeation Chromatography (GPC), separates compounds based on molecular size.

• • CE-SDS Based Molecular Size Variation Analysis Service

  Aggregation or fragmentation of protein molecules primarily causes variations in molecular size, impacting their biological activity, stability, and their efficacy and safety as pharmaceuticals. In the development and production of biopharmaceuticals, even slight variations in molecular size can reduce drug efficacy or pose safety risks. Thus, precise detection and analysis of these variations are crucial for bioproduct characterization.

• • SDS-PAGE Based Protein Molecular Weights Analysis Service

  Molecular size variability is critically important in biological research and medical applications, serving not only in diagnosis and disease prevention but also in the quality control of bioproducts. Electrophoresis, particularly Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis (SDS-PAGE), is revered as the gold standard for this purpose due to its high sensitivity, ease of operation, and broad applicability.