Hyodeoxycholic Acid Analysis Service
- Investigate HDCA metabolic changes in animal liver diseases and metabolic disorders to support veterinary diagnostics and treatment.
- Evaluate the impact of drugs on HDCA metabolism, aiding in new drug development and efficacy assessment.
- Explore HDCA's role in animal lipid metabolism and cholesterol regulation, contributing to nutritional studies.
- Analyze interspecies differences in HDCA metabolism, advancing comparative physiology research.
Hyodeoxycholic acid (HDCA), also known as 3α,6α-dihydroxy-5β-cholan-24-oic acid, is a secondary bile acid and a metabolic byproduct of intestinal bacteria. It differs from deoxycholic acid by the position of the 6α-hydroxyl group at the 12 location. HDCA is predominantly found in the bile of pigs and other mammals, playing a critical role in lipid metabolism and cholesterol regulation. Unlike the more common deoxycholic acid in humans, HDCA constitutes a significant portion of bile acids in pigs and other animals. It is essential for normal digestive functions and is linked to various liver diseases and metabolic disorders. Accurate measurement of HDCA levels and its metabolic status is crucial for understanding its biological functions and potential clinical implications.
HDCA analysis is essential not only for veterinary science and animal health research but also in drug development, nutritional studies, and comparative physiology. By quantifying HDCA, researchers can explore its role in disease development, progression, and treatment, providing valuable data for scientific research and clinical practice.
Figure 1. Molecular Structure of Hyodeoxycholic Acid
MtoZ Biolabs offers Hyodeoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in HDCA detection.
Analysis Workflow
Service Advantages
1. High Sensitivity and Precision
HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of HDCA.
2. Rapid and Efficient
Optimized sample preparation and fast analysis ensure quick and efficient processing.
3. Wide Applicability
Suitable for various biological samples, including blood, urine, feces, and tissues.
4. Accurate and Reliable Data
Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.
Sample Submission Requirements
Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.
Applications
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Hyodeoxycholic Acid
4. Raw Data
5. Custom Analysis Report
Our Hyodeoxycholic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.
How to order?
