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    Glycosylation Protein Analysis Service

      Glycosylation, a critical post-translational modification, plays essential roles in cellular signaling, immune responses, and protein folding and function. At MtoZ Biolabs, we leverage advanced mass spectrometry and bioinformatics to deliver precise analyses of protein glycosylation. Our platform features high-resolution mass spectrometers and sophisticated data analysis software, targeting complex glycan structure identification and quantification.

       

      Our team utilizes state-of-the-art Orbitrap mass spectrometers with HCD and ETD dual fragmentation technologies for effective glycosylation protein analysis. We also deploy Byonic bioinformatics software for meticulous glycopeptide identification and glycan analysis. MtoZ Biolabs is dedicated to providing top-tier glycosylation protein analysis service globally. For any inquiries or specific needs, please contact us. We are committed to enhancing your research outcomes.

       

      Analysis Workflow

      1. Protein extraction and purification.

      2. Glycan release using targeted enzymatic or chemical methods.

      3. Glycopeptide enrichment through diverse chemical and affinity chromatography.

      4. Cutting-edge mass spectrometry analysis.

      5. Detailed bioinformatics evaluation of glycosylation sites and glycan structures.

       

      Service Advantages

      1. High Coverage

      We enhance glycopeptide enrichment and analytical accuracy using affinity chromatography, hydrophilic interaction chromatography, and non-specific enzymatic digestion.

       

      2. Quantitative Precision

      Our protocols, including dimethyl labeling, ensure precise and reproducible measurements.

       

      3. Customized Services

      We tailor our analyses to meet the specific needs of your research and sample types, guaranteeing optimal results.

       

      Applications

      1. Biopharmaceutical Development

      Ensuring the consistency and quality of glycoprotein-based drugs, such as monoclonal antibodies.

       

      2. Disease Biomarker Discovery

      Identifying specific glycosylation changes associated with different cancer types.

       

      3. Vaccine Development

      Monitoring glycosylation changes in response to vaccination to understand immune responses.

       

      Sample Requirements

      We process a wide range of samples: tissue, blood, serum and urine, animal tissues, cells, microbes, proteins.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Glycosylation Protein Analysis

      4. Mass Spectrometry Images

      5. Raw Data

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