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    Feces Metabolomics Service

      Feces metabolomics provides insights into the dynamic interactions between microbial communities, host physiological states, and genetic features by analyzing metabolites found in Feces samples. Rich in both microbial and host-derived metabolites, feces reflect the intestinal microbiome's composition and activity, crucial for understanding both gut health and overall wellness. Utilizing high-resolution mass spectrometry, our analysis accurately measures these metabolites, providing essential data for disease prevention, early diagnosis, and therapeutic approaches.



      Karu, N. et al. Anal Chim Acta. 2018.

      Figure1. Overview of Human Feces Metabolomics


      Services at MtoZ Biolabs

      At MtoZ Biolabs, our high-resolution mass spectrometry techniques form the foundation of a sophisticated Feces metabolomics platform, designed to support both academic research and clinical trials by ensuring precise metabolite identification and quantification.

      Our services include:

      1. Untargeted Analysis

      • Extensive metabolic profiling
      • High-throughput identification of metabolites
      • Metabolic pathway analysis
      • Discovery and validation of novel biomarkers

      2. Targeted Analysis

      (1) Standard curve creation, meticulous preprocessing of raw data, and precise quantification

      (2) Our platform excels in detecting key Feces metabolites, including:

      • Short-chain fatty acids like formate, propionate, valerate, acetate, and butyrate
      • Essential amino acids such as lysine, alanine, glycine, and glutamate
      • Microbial by-products like TMAO and dimethylamine
      • Nutrient-related metabolites such as glucose, lactate, and succinates

      3. Bioinformatics Analysis

      • Assessment of sample quality and analysis of batch effects
      • Detailed metabolite characterization
      • Differential screening of metabolites and multivariate statistical analysis
      • Advanced biomarker research, including pathway and network analysis


      Sample Submission Requirements

      1. Types of Samples

      We process rat feces (dry weight ≥0.02g), mouse feces (dry weight ≥0.02g), and human feces (dry weight ≥0.2g).


      2. Collection and Storage Guidelines

      • Collect Feces samples aseptically using sterile equipment to maintain sample integrity
      • Label and store samples in a cold environment promptly to avoid microbial contamination and chemical breakdown


      3. Pre-treatment Recommendations

      Thoroughly mix fresh Feces samples using a sterile tool prior to freezing to ensure a consistent and representative sample for analysis.


      MtoZ Biolabs is dedicated to providing exhaustive and precise Feces metabolomics services. For specialized metabolite analysis requirements or inquiries not covered by our standard services, please reach out through our inquiry form. Our expert team is ready to offer personalized guidance and tailored solutions to meet your specific research needs.

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