Exosome Sampling Service

The core challenge in exosome research has never been "can it be isolated?" but rather "how to obtain high-activity, low-contamination exosome samples in a stable and efficient manner?" The limitations of traditional methods — time-consuming, labor-intensive, significant batch-to-batch variation, and interference from contaminating proteins — not only affect data reliability but also risk steering research conclusions away from their true biological significance.

 

Services at MtoZ Biolabs

MtoZ Biolabs offers Exosome Sampling Service designed to solve this dilemma! We offer:

✅ Standardized Full Process: Covering sample pretreatment, exosome isolation and purification, strict quality control, and personalized delivery;

✅ Precise Subpopulation Capture: Targeting disease-related markers (e.g., PD-L1, EpCAM) to support liquid biopsy and mechanism research;

✅ Ready-to-use High-Quality Samples: Compatible with downstream RNA sequencing, proteomics, functional validation, and more;

✅ Clinical Translation Support: Compliance assurance from laboratory to industrialization, seamlessly linking diagnostics and drug development.

 

Whether you are new to the exosome field or looking to break through research bottlenecks, we can double your research efficiency with transparent processes, traceable quality control, and flexible delivery!

 

Analysis Workflow

1. Sample Pretreatment and Isolation

• Supported Sample Types: Whole blood/serum/plasma, urine, cerebrospinal fluid, saliva, cell culture media, lavage fluid, etc.;
• Separation Techniques: Ultracentrifugation combined with size exclusion (basic option, suitable for large sample volumes); Magnetic bead sorting (target specific markers to capture low-abundance exosome subpopulations); Polymer precipitation optimization (quick enrichment for small sample volumes).

 

2. Multidimensional Quality Control Validation

• Size and Concentration: Ensuring compliance with the standard exosome range (30–150 nm);
• Marker Detection: Identification of positive markers (CD9/CD63/CD81) and negative markers (Calnexin);
• Contaminant Screening: Strict exclusion of polymer residues, free proteins, and nucleic acid interference.

 

3. Personalized Delivery Packages

• Basic Delivery Package: High-purity exosome suspension (stored in PBS with freeze-thaw suggestions);
• Advanced Analysis Package: Additional RNA integrity reports, protein pre-separation, functional validation experimental designs;
• Compliance Documentation: Including SOPs, raw data, and ethical review support files.

 

Why Choose MtoZ Biolabs

1. Dual Assurance of Purity and Activity

Our patented purification technology combined with low-temperature processing ensures exosome membrane integrity >95%, with contaminant residues reduced by more than 50% compared to industry standards!

 

2. Full Transparency and Traceability

We provide experimental records for every step and support raw data downloads-no worries during manuscript review!

 

3. Flexible Scene Adaptation

• Expert in Small Samples: Efficient processing of difficult samples like cerebrospinal fluid (≥200 μL) and puncture fluid;
• Industrial-Grade Stability: For orders of 50 or more, batch-to-batch consistency CV <10%, accelerating clinical translation.

 

Applications

1. Cancer Early Screening and Efficacy Monitoring

• Enrichment of PD-L1⁺ exosomes to analyze mechanisms of immune therapy resistance;
• Dynamic tracking of exosomal miRNA in patient serum to predict recurrence risks.

 

2. Neurological Disease Research

• Aβ/Tau protein detection in cerebrospinal fluid exosomes to assist in the early diagnosis of Alzheimer's disease;
• Neuronal exosomal miRNA delivery to explore new targets for neural repair.

 

3. Drug Delivery System Development

• Efficient loading of chemotherapy drugs/siRNA into exosomes to verify in vivo targeting efficiency;
• Development of mRNA vaccine exosome carriers, optimizing delivery stability.

 

Sample Submission Suggestions

1. Submit Your Request Online

• Fill out the sample type, volume, and downstream usage in 5 minutes to get your exclusive service code;
• Free Pre-screening Consultation: Our technical team will contact you within one hour to optimize the plan design.

 

2. Cold-chain Sample Shipping

• Use MtoZ Biolabs' free insulated shipping box (available in 2–8°C or -20°C options) with real-time tracking;
• Global sample reception supported.

 

3. Acceptance and Worry-Free After-Sales

• 3-6 Week Delivery: Exosome samples + full quality control report;
• One-month Data Inquiry Period: If you have questions about the results, our technical team will recheck for free and provide solutions.

 

MtoZ Biolabs promises: with laboratory-level rigor, industrial-level efficiency, and clinical-level quality, we will clear the technical obstacles for your exosome research. Choosing us means not just choosing a sample but ensuring data reliability, time control, and accelerated result translation! Submit your request now and take your research to the next level!