Diethyl Malonate Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Diethyl malonate is an organic compound with the molecular formula C₇H₁₂O₄, belonging to the ester class of compounds. Its structure consists of malonic acid's carboxyl groups combined with two ethyl (–CH₂CH₃) groups. Diethyl malonate is typically a colorless liquid with a faint odor and is soluble in many organic solvents. It is widely used in organic synthesis, often serving as an intermediate in the production of pharmaceuticals, fragrances, dyes, and other fine chemicals. Therefore, studying the metabolism of diethyl malonate and its metabolites in the body is of great significance for drug development.
Analyzing the absorption, distribution, metabolism, and excretion (ADME) of diethyl malonate in the body helps to understand its mechanism of action, toxicity, and safe dosage in drug development. The accumulation or transformation of diethyl malonate's metabolites in the body may affect drug efficacy and side effects. Thus, analyzing diethyl malonate and its metabolites can assist in optimizing drug formulations and ensuring safety. Gas chromatography (GC) is commonly used for the quantitative analysis of diethyl malonate. Due to its volatility, the sample can be vaporized, and diethyl malonate is separated between the stationary and mobile phases, allowing for precise quantitative analysis. High-performance liquid chromatography (HPLC) can also be used to detect diethyl malonate in complex matrices. When combined with UV or fluorescence detectors, HPLC efficiently separates and accurately quantifies diethyl malonate. Mass spectrometry (MS) provides a more precise identification of diethyl malonate's molecular structure and mass information. MS is especially effective in analyzing diethyl malonate metabolites or complex mixtures.
Figure 1. The Structure of Diethyl Malonate
Our Diethyl Malonate Analysis Service at MtoZ Biolabs employs the power of our sophisticated liquid chromatography-mass spectrometry (LC-MS) platform and the experience of our professional metabolomics team. We offer an exhaustive diethyl malonate analysis, ensuring superb sensitivity and precision.
Analysis Workflow
Service Advantages
Applications
1. Discovering new disease biomarkers
2. Enhancing disease diagnosis
3. Speeding up the discovery of innovative therapeutics
4. Uncovering new insights into disease mechanisms
Sample Submission Requirements
1. Sample Types
Human serum, plasma, urine, tissues, and other biological samples. A minimum of 3 materials with identical conditions is required for each sample.
2. Sample Volume
3. Sample Preservation
Samples should be stored at -80°C to ensure stability.
Note: Please provide detailed information about sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Comprehensive Information on Diethyl Malonate
4. Raw Data
5. Custom Analysis Report
With our diethyl malonate analysis service, MtoZ Biolabs strives to support your research and product development by providing precise and dependable results.
How to order?
