Dehydrocholic Acid Analysis Service

Dehydrocholic acid (DHCA) is a triketone bile acid synthesized through the oxidation of cholic acid. It is primarily used as a choleretic agent to enhance bile secretion and flow, aiding in the treatment of cholestasis and other liver and gallbladder diseases. DHCA's unique triketone structure gives it distinct chemical properties and biological functions. Analyzing DHCA is essential for understanding its therapeutic mechanisms, evaluating drug efficacy, and studying bile acid metabolic pathways.

 

Figure 1. Molecular Structure of Dehydrocholic Acid

 

MtoZ Biolabs offers Dehydrocholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in DHCA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

HPLC-MS technology can detect very low concentrations of DHCA in samples, ensuring accurate detection of trace components.

 

2. High Specificity

Mass spectrometry's mass-to-charge ratio (m/z) analysis effectively distinguishes DHCA from other bile acids, providing precise chemical structure information.

 

3. Precise Quantification

Rigorous quantification methods ensure the accuracy and reproducibility of data.

 

4. Rapid Analysis

Efficient sample processing and detection procedures allow for high-throughput analysis of large sample volumes.

 

Sample Submission Requirements

 



For detailed sample submission instructions, please consult our technical team.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Dehydrocholic Acid

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into DHCA's extensive physiological roles through top-tier analytical techniques and expert services.