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    BPG Analysis Service

      BPG (2,3-bisphosphoglycerate) is a small molecule with the chemical formula C₃H₈O₁₀P₂. Its molecular structure contains two phosphate groups located on the second and third carbon atoms. BPG is a key metabolite produced in red blood cells that participates in regulating the affinity of hemoglobin for oxygen, directly affecting oxygen supply to tissues. Changes in its concentration can indicate alterations in oxygen transport capacity. The presence of BPG enables hemoglobin to release oxygen more effectively in low-oxygen environments, thereby playing an important role in both physiological and pathological states. Research indicates that BPG levels are associated with various diseases, including anemia, cardiovascular diseases, and diabetes, making it a potential biomarker. 

       

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      Figure 1. The Structure of BPG

       

      BPG detection is typically performed using mass spectrometry (MS) and high-performance liquid chromatography (HPLC). These techniques provide high sensitivity and specificity for the quantitative analysis of BPG in biological samples. At MtoZ Biolabs, we offer a superior BPG Analysis Service, leveraging our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and a team of seasoned metabolomics experts. Our service delivers a comprehensive analysis of BPG, ensuring utmost sensitivity and precision.

       

      Analysis Workflow 

       

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      Service Advantages

      • Extensive experience in various biological sample preparation techniques
      • Professional standard operating procedure
      • State-of-the-art facilities and equipment for precise analysis
      • Expert team with extensive experience in metabolomics
      • Comprehensive data analysis
      • Excellent customer service and after-service support

       

      Applications

      • Discovery of novel disease biomarkers
      • Improvement of disease diagnostic processes
      • Acceleration in the discovery of groundbreaking therapeutic solutions
      • Acquisition of new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. For each sample, it's required to select more than 3 materials under the same condition. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C to maintain stability.

       

      Note: Details on sample collection and handling should be provided.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on BPG

      4. Raw Data

      5. Customized Analysis Report

       

      Our BPG analysis service aims to streamline your research and product development processes, delivering accurate, dependable results that you can rely on.

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