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    α-KIC Analysis Service

      α-KIC (α-Ketoisocaproic acid) is a keto acid compound with the chemical structure C₆H₁₀O₃, consisting of a keto group and an isocaproic acid group. It primarily originates from leucine metabolism and is the product of leucine deamination, widely found in the human body and other organisms. α-KIC plays an important role in biological activity, participating in energy metabolism, promoting protein synthesis, and helping to maintain muscle function. Its metabolites include isovaleric acid, which is crucial in energy production and amino acid metabolism balance. Analyzing the content of α-KIC and its metabolites in plant and biological samples can reveal their roles in metabolic regulation, nutritional balance, and disease diagnosis, providing essential scientific insights for metabolic disease research and health management.

       

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      Figure 1. The Structure of α-KIC

       

      MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs is proficient in the analysis of α-KIC, utilizing a cutting edge LC-MS-based metabolomics research platform. Our specialized service ensures the accuracy and precision in quantifying α-KIC and its metabolites, as well as in the identification of myriad metabolites. If you are interested in our α-KIC analysis service, please feel free to contact us at any time. We are dedicated to providing high-quality analytical services and technical support.

       

      Analysis Workflow 

       

      1846742628495380480-Workflowofα-KICAnalysisService.PNG

       

      Service Advantages

      1. Advance Analysis Platform: MtoZ Biolabs established an advanced α-KIC analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

       

      2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

       

      3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all α-KIC analysis data, delivering clients a detailed and comprehensive data report.

       

      4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.

       

      Applications

      • Discovering new disease biomarkers  
      • Enhancing disease diagnosis  
      • Speeding up the discovery of innovative therapeutics  
      • Uncovering new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      We accept a variety of biological samples such as serum, plasma, urine, tissues etc. However, it is recommended to provide more than 3 materials with the same condition for each sample.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      It is required to store the samples at -80°C to maintain stability.

       

      Note: Please provide detail on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. LC and MS Parameters Relevant to α-KIC Analysis

      3. Detailed Information on α-KIC

      4. Raw Data

      5. Custom Analysis Report

       

      Our α-KIC analysis service aims to facilitate your research and product development by providing accurate and reliable data. We look forward to aiding your understanding of the role α-KIC plays in various biological processes and its potential as a therapeutic target.

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