9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic Acid Analysis Service

Prostaglandin E2 (PGE2), also known as 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, is a naturally occurring prostaglandin with critical roles in various physiological and pathological processes. PGE2 is synthesized from arachidonic acid (AA) through the cyclooxygenase (COX) pathway, beginning with AA activation by phospholipase A2. The COX enzymes convert AA into prostaglandin endoperoxides, first producing prostaglandin G2 (PGG2) and then prostaglandin H2 (PGH2), which is subsequently transformed into PGE2 by specific synthases. This prostaglandin is widely recognized for its involvement in inflammation, vasodilation, and the regulation of smooth muscle function.

 

PGE2 is notable for its roles in reproductive health, including labor induction and cervical ripening, as well as its use in managing postpartum hemorrhage and terminating pregnancies. Additionally, PGE2 is essential in neonatal care, particularly in maintaining ductus arteriosus patency in infants with congenital heart defects prior to surgical intervention. Its effects on the immune system and inflammation make it a target of interest in the study of various diseases, including asthma, cardiovascular conditions, and cancers. In terms of its mechanism of action, PGE2 binds to specific prostaglandin receptors (EP receptors), leading to diverse effects, including the softening of the cervix, uterine contraction, and vasodilation. However, its therapeutic use is accompanied by potential side effects such as nausea, vomiting, diarrhea, and uterine hyperstimulation.

 



 

Figure 1. The Structure of 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic Acid

 

Given its broad physiological roles and therapeutic applications, the study of PGE2 is crucial for advancing our understanding of inflammation, immune response, and reproductive health. MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. At MtoZ Biolabs, we offer a comprehensive 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid analysis service, designed to address the following challenges:

• Precise quantification of 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid in various sample types
• Detailed metabolomic profiling for in-depth biological interpretation
• High-quality data for biomarker discovery and validation

 

Analysis Workflow

 



 

Service Advantages

1. Advance Analysis Platform

MtoZ Biolabs established an advanced 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.

 

2. One-Time-Charge

Our pricing is transparent, no hidden fees or additional costs.

 

3. High-Data-Quality

Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid analysis service data providing clients with a comprehensive data report.

 

4. Fast Turnaround

The process from sample handling to report generation is efficient, shortening the analysis cycle.

 

Applications

Our 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid analysis service can support:

• Disease biomarker discovery and validation
• Drug efficacy and toxicity studies
• Mechanistic studies of disease pathogenesis

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is advised to prepare more than 3 biological replicates.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic Acid

4. Raw Data

5. Custom Analysis Report

 

Contact us today to learn how our 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid analysis service can advance your research!