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    9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic Acid Analysis Service

      9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid, commonly known as Prostaglandin E1 (PGE1), is a biologically active metabolite derived from the cyclooxygenase (COX) metabolism of dihomo-γ-linolenic acid (DGLA). In normal human or animal plasma, PGE1 is generally undetectable due to its rapid metabolism, yet it plays significant physiological roles. PGE1 is one of the major prostaglandins found in human semen, and its pharmacological effects include vasodilation, blood pressure reduction, and inhibition of platelet aggregation. Clinically, PGE1 is often used as a vasodilator and platelet aggregation inhibitor.

       

      PGE1 exerts multiple therapeutic effects. It can inhibit ADP-induced human platelet aggregation, demonstrating its strong anti-platelet properties. Its vasodilatory and antihypertensive actions make it useful in treating male sexual dysfunction and as an adjunct to cardiac drugs in emergency neonatal care. PGE1 is used therapeutically for maintaining the patency of the ductus arteriosus in newborns with congenital heart defects. In severe cases of limb ischemia, PGE1 is applied to stimulate angiogenesis by dilating blood vessels and promoting blood flow to the affected areas, providing critical support in vascular regeneration. Additionally, PGE1 influences various cellular signaling pathways, including protein kinase C (PKC), adenylate cyclase activity, and calcium ion mobilization, contributing to its wide range of physiological effects.

       

      1846756931650834432-TheStructureof9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oicAcid.png

       

      Figure 1. The Structure of 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic Acid

       

      Given the significant roles of PGE1 in both clinical and physiological contexts, accurate quantification of this prostaglandin is essential for research into its therapeutic applications and biological mechanisms. MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. At MtoZ Biolabs, we provide comprehensive analysis services for 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic Acid. Our experienced team utilizes a wide range of sophisticated techniques including liquid chromatography-mass spectrometry (LC-MS) to provide high-quality, accurate, and reliable data for your research. 

       

      What Can MtoZ Biolabs Do for You?

      • Detailed metabolite profiling: Accurate identification and quantification of 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic Acid.
      • Metabolic pathway investigation: Understand the metabolic pathways of this prostaglandin in different physiological and pathological conditions.
      • Biomarker discovery: Discover potential biomarkers related to diseases or drug response.

       

      Analysis Workflow

       

      1846755923554062336-Workflowfor9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oicAcidAnalysisService.png

       

      Service Advantages

      1. Advance Analysis Platform

      MtoZ Biolabs established an advanced 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.

       

      2. One-Time-Charge

      Our pricing is transparent, no hidden fees or additional costs.

       

      3. High-Data-Quality

      Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid analysis service data providing clients with a comprehensive data report.

       

      4. Fast Turnaround

      The process from sample handling to report generation is efficient, shortening the analysis cycle.

       

      Applications

      Our service can facilitate your research in the following areas:

      • Drug development
      • Biochemical pathway analysis
      • Disease biomarker discovery

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. It is advised to prepare more than 3 biological replicates.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Storage and Shipping

      Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic Acid

      4. Raw Data

      5. Custom Analysis Report

       

      At MtoZ Biolabs, we are committed to providing high-quality, accurate, and reliable metabolomics services to aid in your research. Contact us today to learn more about our 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic Acid Analysis Service.

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