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    5-Methoxytryptamine Analysis Service

      5-Methoxytryptamine (5-MT) is an endogenous amine belonging to the tryptamine family, derived from the methylation of 5-hydroxytryptamine (5-HT, serotonin). Its chemical structure consists of an indole ring with a methoxy group attached at the 5th position and an ethylamine side chain with a terminal amino group. Due to this structural characteristic, 5-methoxytryptamine can interact with various neurotransmitter receptors, particularly serotonin (5-HT) receptors, exerting biological effects within the nervous system. In the body, 5-methoxytryptamine is primarily metabolized through oxidative deamination, forming 5-methoxyindoleacetic acid (5-MIAA), with most of the metabolism occurring in the liver, and subsequently excreted in the urine. Given its role as a neuromodulator in the central nervous system, 5-methoxytryptamine is involved in regulating physiological processes such as mood, sleep cycles, and thermoregulation.

       

      Metabolomics analysis of 5-methoxytryptamine utilizes high-throughput techniques such as mass spectrometry and nuclear magnetic resonance to comprehensively study its dynamic changes and metabolic pathways within the body. This analytical approach is essential for elucidating the biological functions of 5-methoxytryptamine, optimizing its clinical applications in the treatment of neurological disorders, evaluating the impact of its excess or abnormal metabolism on health, and advancing personalized medical interventions.

       

      1831212075218227200-TheStructureof5-Methoxytryptamine.png

      Figure 1. The Structure of 5-Methoxytryptamine

       

      MtoZ Biolabs provides a top-notch 5-Methoxytryptamine (5-MT) Analysis Service, supported by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and highly skilled metabolomics team. Our service delivers a thorough analysis of 5-MT, maintaining superior sensitivity and precision. 

       

      Analysis Workflow

       

      1831212157661466624-Workflowof5-MethoxytryptamineAnalysisService.PNG

       

      Service Advantages

       

      Applications

      • Qualitative analysis of 5-MT metabolites
      • Quantitative analysis of 5-MT content
      • Essential for pharmaceutical and therapeutic research

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. At least three similar-conditioned materials should be selected for every sample.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C to ensure stability.

       

      Note: Please provide details about sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 5-Methoxytryptamine

      4. Raw Data

      5. Custom Analysis Report

       

      Our 5-Methoxytryptamine Analysis Service strives to assist your research and product development initiatives by supplying precise and reliable results. 

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