5,6-Dihydroxyindole-2-Carboxylic Acid Analysis Service

5,6-dihydroxyindole-2-carboxylic acid (DHICA) is a metabolite in the melanin biosynthesis pathway, particularly formed during the metabolism of indole derivatives such as L-DOPA and tyrosine. DHICA is primarily involved in the production of eumelanin, a type of melanin pigment, and plays a crucial role in pigmentation. Measuring the levels of DHICA in biological samples can reflect an individual's melanin production and their ability to synthesize eumelanin. In metabolomics research, DHICA is often used as a biomarker for the melanin biosynthesis pathway. Clinically, detecting DHICA can be used to assess a patient's melanin production, guiding interventions for pigmentation disorders. When studying the interactions between drugs and melanin synthesis, DHICA as a metabolite can help in understanding the impact of drugs on melanin production.

 



Figure 1. The Structure of 5,6-Dihydroxyindole-2-Carboxylic Acid

 

Leveraging our advanced liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team, MtoZ Biolabs offers a top-tier 5,6-Dihydroxyindole-2-Carboxylic Acid Analysis Service. Our service ensures a thorough analysis of 5,6-dihydroxyindole-2-carboxylic acid with high sensitivity and accuracy.

 

Analysis Workflow 

 



 

Service Advantages

1. Advanced Technological Platform

We use industry-leading mass spectrometry equipment and analysis techniques to ensure high precision and reliability of the analysis results.

 

2. Extensive Experimental Experience

With years of experience in experimental operations and data processing, we can handle various complex biological samples.

 

3. Rapid Data Delivery

Ensure quick sample processing and timely delivery of research results to facilitate scientific progress.

 

Applications

• Qualitative analysis of the metabolites of DHICA
• Quantitative analysis of DHICA content
• Provide basis for improvement in related research and development fields

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues and other biological samples. At least three samples of the same condition are required for each material. 

 

2. Sample Volume

At least 200 μL of liquid sample; At least 200 mg of solid tissues.

 

3. Sample Preservation

All the samples should be stored at -80°C to maintain stability.

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 5,6-Dihydroxyindole-2-Carboxylic Acid

4. Raw Data

5. Custom Analysis Report

 

At MtoZ Biolabs, we strive to expedite your research and product development by delivering precise and trustworthy analysis results through our 5,6-Dihydroxyindole-2-Carboxylic Acid Analysis Service.