15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic Acid Analysis Service

15S-Hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid, also known as Prostaglandin B2 (PGB2), is a bioactive lipid derived from membrane phospholipids, belonging to the prostaglandin family. Structurally, PGB2 is a C20 unsaturated fatty acid with a cyclopentane ring, and it plays key roles in various physiological processes, including immune regulation, inflammation, and vascular function. It is one of the most abundant prostaglandins released by osteoblasts and is known for its inhibitory effect on glucagon-stimulated cAMP accumulation in hepatocytes.

PGB2 has garnered attention for its role in immune modulation, where it inhibits the proliferation of dendritic cells (DC) and T cells, and acts as an activator of thromboxane A2 receptors (TXA2R). Additionally, PGB2 induces vasoconstriction in canine skin blood vessels, highlighting its impact on vascular dynamics. These characteristics make it a significant target in studies exploring prostaglandin-mediated signaling, immune response, and potential therapeutic applications. Given its broad biological activity, PGB2 is extensively studied in relation to inflammatory diseases, immune disorders, and cancer. Its ability to modulate immune responses and affect cell communication underscores its importance in both normal physiology and disease states.

Figure 1. The Structure of 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic Acid

MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. At MtoZ Biolabs, we offer comprehensive 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid analysis service utilizing advanced LC-MS/MS technologies, providing you with:

• Reliable and accurate quantification of 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid
• Detailed metabolic pathway analysis
• Comparative analysis between different biological samples

Analysis Workflow

Service Advantages

1. Advance Analysis Platform

MtoZ Biolabs established an advanced 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.

2. One-Time-Charge

Our pricing is transparent, no hidden fees or additional costs.

3. High-Data-Quality

Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid analysis service data providing clients with a comprehensive data report.

4. Fast Turnaround

The process from sample handling to report generation is efficient, shortening the analysis cycle.

Applications

Our service can be applied in:

• Biomarker discovery for disease diagnosis and prognosis
• Drug target identification and validation
• Basic research in understanding the physiological function and regulation of 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is advised to prepare more than 3 biological replicates.

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

Note: Please provide details on sample collection and handling.

Deliverables

1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic Acid

4. Raw Data

5. Custom Analysis Report

Contact us today to learn more about how we can assist you in your research journey.