Resources

Proteomics Databases



Metabolomics Databases

• • Principle of Peptide Mass Fingerprinting

  Peptide mass fingerprinting (PMF) has emerged as a powerful technique in proteomics, enabling researchers to identify proteins with high precision and efficiency. This method leverages mass spectrometry to analyze peptide masses derived from protein digests, providing a unique "fingerprint" that can be matched against protein databases.

• • Mechanism of Membrane Protein Identification

  Membrane proteins play critical roles in numerous cellular functions, including signaling, transport, and communication. Understanding their mechanisms and identifying these proteins is essential for advancing biomedical research and therapeutic development. However, the study of membrane proteins is fraught with challenges due to their hydrophobic nature and low abundance.

• • Application of Membrane Protein Identification

  Membrane proteins are pivotal to numerous cellular functions, including signal transduction, transport, and cell communication. Understanding and identifying these proteins is crucial for advancing biomedical research and developing new therapeutic strategies.

• • Workflow of Membrane Protein Identification

  Membrane proteins play critical roles in various cellular processes, including signal transduction, transport, and cell-cell communication. Identifying and characterizing these proteins is crucial for understanding their functions and their implications in health and disease. However, membrane proteins present unique challenges due to their hydrophobic nature and low abundance.

• • What Data Does Circular Dichroism Primarily Measure?

  Circular Dichroism (CD) spectroscopy, also known as circular dichroism spectroscopy, is a spectral technique used to analyze chiral compounds, particularly the structure and dynamics of biomolecules such as proteins and nucleic acids. CD spectroscopy provides information about molecular structure (such as protein secondary structure), conformational changes, and intermolecular interactions.

• • Amino Acid Determination: Precise Content Analysis

  Amino acid determination has important applications in many biochemical and biomedical research. For example, it can be used to determine the amino acid composition of proteins, helping researchers understand the structure and function of proteins. In addition, amino acid determination can also be used to monitor the levels of amino acids in biological samples, which is crucial for studying the pathogenesis and treatment effects of various diseases.

• • Amino Acid Composition Detection: Revealing the Biological Code

  The DNA in the organism is the foundation of life, containing genetic information. However, DNA does not directly participate in the process of protein synthesis in the organism, but is transformed into proteins through the processes of transcription and translation. In the process of protein synthesis, amino acids play an important role. Amino acids are the basic units that make up proteins, and different combinations of amino acids form different proteins, which is called the genetic code.

• • The Best Dilution Strategy for HCP Detection

  HCP (Host Cell Protein) is a protein impurity that may remain in the production process of biopharmaceuticals, originating from the host cells used for producing these drugs. The presence of HCP can potentially impact the safety, efficacy, and quality of the drugs, therefore requiring strict detection and control. Different HCP detection methods have varying sensitivities and specificities, thus the optimal dilution strategy may differ.

• • Antibody Drug Microflow Imaging Particle Analysis

  Antibody drugs are a class of biopharmaceuticals that utilize the immune system's mechanism of specific recognition and binding to specific targets in the body. They are widely used in the treatment of various diseases, such as cancer, autoimmune diseases, and infectious diseases. Due to their importance in clinical therapy, ensuring the quality, purity, activity, and safety of antibody drugs is crucial.

• • Analysis of Recombinant Protein Drugs with FcyRI/FcyRII/FcyRIII Interactions

  Recombinant protein drugs are protein products derived from animals and plants through biotechnological research and development, which possess certain biological activities and can prevent and treat human, animal, and plant diseases. Compared to small molecule drugs, recombinant protein drugs have advantages such as high activity, high specificity, and low toxicity, making them favored by researchers.