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    Amino Acids Analysis Service

      Amino acids, essential components of biomolecules, are not only the building blocks of proteins but also play pivotal roles in cellular metabolism, signal transduction, and energy transformation. Amino acid analysis evaluates the amino acid content in biological samples both quantitatively and qualitatively, providing vital insights for diagnosing diseases, assessing nutritional status, and advancing biotechnological research. As science progresses, Amino acid analysis has become crucial in metabolomics, enabling researchers to explore alterations in metabolic pathways and disease mechanisms.

       

      MtoZ Biolabs employs high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) for amino acid analysis, a method noted for its exceptional resolution and sensitivity. This technique not only encompasses a comprehensive spectrum of amino acids but also investigates the nuanced changes within their metabolic pathways, substantially supporting life sciences research.

       

      Analysis Workflow

       

      1808776071807094784-11947_2024_3448_Figa_HTML.webp 

      Cheng, H. et al.Food Bioproc Tech. 2024.

      Figure 1. Based on Amino Acid Metabolomics Analysis by LC-MS

       

      Services at MtoZ Biolabs

      Amino Acid Flux Analysis

      Quantify the dynamic changes of amino acids in cellular metabolic pathways, revealing their bioavailability and transformation processes.

       

      Comprehensive Analysis of Amino Acid Metabolites

      In-depth analysis and quantification of amino acid metabolites, including related intermediates.

       

      Stable Isotope Labeling Studies

      Apply stable isotope labeling techniques to track the dynamic changes of specific amino acids in metabolic networks.

       

      Disease-related Amino Acid Metabolic Analysis

      Conduct in-depth studies on amino acid metabolism changes associated with various disease states, such as metabolic and neurodegenerative diseases.

       

      Amino Acid Turnover Studies

      Evaluate the turnover rates by measuring the synthesis and degradation rates of amino acids.

       

      Customized Amino Acid Metabolic Studies

      Provide customized amino acid analysis solutions based on specific client needs.

       

      Service Advantages

      • High Sensitivity and Precision: Capable of detecting amino acids down to the picomolar level.
      • Rapid Analysis: The entire process from sample handling to result output can be completed within a few hours.
      • Broad Application Range: Suitable for various biological samples including clinical samples, food samples, and plant and animal tissues.

       

      Applications

      Clinical Diagnosis: Assist in diagnosing metabolic diseases such as liver and kidney diseases by analyzing the concentration changes of specific amino acids.

       

      Nutritional Research: Assess individual nutritional statuses and optimize dietary plans.

       

      Biopharmaceuticals: Monitor and optimize amino acid levels in bioreactors to improve production efficiency.

       

      Basic Research: Study the metabolic pathways of amino acids in organisms, revealing their relationship with diseases and health status.

       

      Sample Results

      Metabolomic Analysis of Amino Acids in Psoriasis

      1808776423298158592-结果.png

      Chen, C. et al. Theranostics. 2021.

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