Resources

Proteomics Databases



Metabolomics Databases

• • What Is Mass Spectrometry-Based Histone Succinylation Analysis?

  Histone succinylation (Ksucc), as an emerging epigenetic modification, has attracted considerable attention in life science research in recent years. It not only reflects dynamic changes in chromatin architecture but also provides insight into cellular metabolic states and disease mechanisms. Mass spectrometry has therefore become a core analytical tool for investigating histone succinylation. Scientific Background of Histone Succinylation 1. Chemical Characteristics and Mechanisms of Action Histone ......

• • What Is Protein Terminal Sequencing?

  Protein terminal sequencing is a critical analytical approach for characterizing the amino-terminal (N-terminus) and carboxyl-terminal (C-terminus) sequences of proteins, playing an essential role in understanding protein structure, biological function, and post-translational modifications. Terminal sequences not only influence protein spatial folding and molecular interaction capabilities, but also reflect maturation status and post-translational processing events. Through terminal sequencing, resear......

• • What Is Antibody Glycosylation?

  Learn what antibody glycosylation is, where glycans attach on IgG molecules, and why Fc glycosylation matters for antibody heterogeneity and characterization.

• • Top-Down vs. Bottom-Up Proteomics: Key Differences and When to Use Each

  Compare top-down and bottom-up proteomics by structural resolution, sample complexity, proteoform context, and project fit for discovery, biologics, and proteoform analysis workflows.

• • Step-by-Step LC-MS Peptide Mapping

  Follow a practical LC-MS peptide mapping workflow from sample preparation through digestion, LC-MS/MS analysis, database search, and coverage reporting for biologics characterization.

• • Step-by-Step Glycan Analysis of a Biologic Therapeutic

  Follow a step-by-step glycan analysis workflow for biologic therapeutics from sample feasibility through method selection, LC-MS/MS analysis, and validation planning.

• • The Role of Antibody Glycosylation in Its Functionality

  Learn how antibody glycosylation affects Fc function, effector activity, stability, and comparability, and how glycan analysis supports functional interpretation in biologics development.

• • Released N-Glycan Profiling vs. Glycopeptide Mapping for Antibody Glycosylation Analysis

  Compare released N-glycan profiling and glycopeptide mapping for antibody glycosylation analysis by structural resolution, site linkage, deliverables, and project fit for mAb comparability and site-specific review.

• • Peptide Sequencing: Techniques and Applications

  Learn how peptide sequencing determines amino acid sequences using LC-MS/MS, de novo sequencing, and Edman degradation, plus key applications in proteomics and biopharmaceutical analysis.

• • Peptide Sequencing: Methods, Applications, and Advances in Proteomics

  Explore peptide sequencing methods in proteomics, including database search, de novo sequencing, key applications, and recent advances in protein identification and PTM mapping.