Resources

Proteomics Databases



Metabolomics Databases

• • Why Was the Target Protein Not Detected by IP-MS?

  Target missing from IP-MS? Learn whether IP enrichment failed or MS detection limits apply, and how to diagnose antibody, lysis, wash, and search issues.

• • Which Controls Are Needed for an IP-MS Experiment?

  Learn which controls IP-MS needs, including isotype IgG, bead-only, and treatment-matched arms, and how to match controls to antibody design and study goal.

• • Can Immunoprecipitation Eluates Be Submitted Directly for Mass Spectrometry?

  IP eluates can be submitted for LC-MS/MS when controls, buffers, and labels are ready. Learn what direct submission means and when prep is required first.

• • IP-MS vs Co-IP Western Blot: Which Method Fits Your Study?

  Compare IP-MS and Co-IP western blot for interaction studies. See when MS discovery fits, when targeted WB confirmation is enough, and when to use both.

• • What Is Immunoprecipitation Mass Spectrometry and When Is It Used?

  Learn what IP-MS is, how it differs from Co-IP and AP-MS, and when immunoprecipitation mass spectrometry fits endogenous bait interaction projects.

• • How to Prepare Immunoprecipitation Samples for Mass Spectrometry

  Prepare IP samples for LC-MS/MS with matched isotype controls, buffer-compatible digestion, peptide cleanup, and metadata for IP-MS interaction analysis.

• • What Is Exosome Proteomics Service and When Should You Use It?

  A service guide explaining what exosome proteomics is, when to request an Exosome Proteomics Service or EV Proteomics Service, and what to confirm before submission.

• • Extracellular Vesicle Proteomics Service: From EV Protein Profiling to Comparative Analysis

  A service-oriented guide to extracellular vesicle proteomics covering EV protein profiling, comparative EV proteomics analysis, and how EV search terms map to exosome proteomics workflows.

• • How to Choose an AP-MS Service Provider for Your Project

  Compare AP-MS providers by scope, control design support, deliverables, and consultation. See what to prepare and which questions to ask before outsourcing.

• • How to Identify High-Confidence Interactors from AP-MS Data

  Learn how to rank high-confidence interactors from AP-MS using control contrast, replicate support, enrichment scoring, and validation-ready shortlist criteria.