Resources

Proteomics Databases



Metabolomics Databases

• • Droplet-Based Single Cell RNA Sequencing

  Droplet-based single cell RNA sequencing is designed to resolve comprehensive RNA expression profiles at the single-cell level. The core of this technology lies in its ability to capture intracellular transcripts with exceptionally high resolution. By encapsulating individual cells in microdroplets for isolated RNA amplification and sequencing, researchers can detect unique gene expression signatures of single cells. This technique holds significant value in biomedical research.   In cancer research, ......

• • Single Cell Discoveries

  Single cell discoveries refer to the use of high-throughput omics technologies at the single-cell level to uncover heterogeneity and dynamic changes among individual cells in gene expression, epigenetic modifications, transcriptional activity, and more. This enables precise interpretation of tissue complexity, biological functional states, and disease mechanisms. The field has advanced rapidly in recent years, with representative technologies including single-cell RNA sequencing (scRNA-seq), single-ce......

• • Cryo Single Particle Analysis

  Cryo single particle analysis is a technique that utilizes cryo-electron microscopy (Cryo-EM) to determine the three-dimensional structures of biological macromolecules such as proteins in a near-native state. Unlike crystallography, it does not require crystal formation or molecular fixation, and it is capable of capturing diverse conformational states of individual particles at near-atomic resolution for 3D reconstruction. This method has become a pivotal tool in structural biology and molecular med......

• • Single Molecule Long Read Sequencing

  Single molecule long read sequencing is a genomic sequencing technology that obtains complete sequence information by analyzing individual DNA molecules. This approach has demonstrated broad application potential in genome assembly and structural variant detection. Owing to its ability to produce long reads, the technology is particularly effective in resolving complex genomic architectures, thereby improving the continuity and completeness of genome assemblies.   In the field of structural variation ......

• • Spatial Single Cell Sequencing

  Spatial single cell sequencing enables the genomic and transcriptomic analysis of individual cells within their spatial context in tissues. The emergence of this technology has introduced a new perspective for scientific research, allowing investigators to more precisely explore cellular behavior and interactions within their native microenvironments. By integrating spatial information with single-cell gene expression data, researchers can more comprehensively uncover mechanisms of cell fate determina......

• • Spatial Transcriptome Sequencing

  Spatial transcriptome sequencing is an advanced high-throughput sequencing technology that integrates spatial positional information with gene expression data to precisely map the distribution of mRNA within tissue sections. This technique overcomes the limitations of traditional single-cell transcriptome sequencing, which fails to retain spatial context, thereby enabling researchers to not only uncover heterogeneity in gene expression across cells but also to localize these differences within the tis......

• • Deciphering Molecular Interactions by Proximity Labeling

  Deciphering molecular interactions by proximity labeling is an emerging technological approach aimed at investigating interactions between biomolecules. Molecular interactions within living organisms are critical for maintaining biological functions, and understanding their mechanisms is essential for revealing the nature of numerous biological processes, thereby advancing disease diagnosis and treatment. Proximity labeling enables researchers to identify and study molecular interaction partners in co......

• • 10x Genomics Single Cell RNA-Seq

  10x Genomics single cell RNA-seq is a high-throughput single-cell transcriptome sequencing platform developed by 10x Genomics, based on droplet microfluidics technology. This technique enables the in situ labeling and sequencing of RNA molecules from tens of thousands of individual cells in a single experiment, thereby reconstructing the cellular composition, subpopulation distribution, and gene expression profiles of complex tissues at single-cell resolution. This groundbreaking approach has fundamen......

• • Single B Cell Screening

  Single B cell screening is an advanced and rapidly evolving technology that has gained significant traction in recent years for antibody drug development and immunological research. This technique enables the isolation and analysis of individual B cells at the single-cell level, allowing for the identification of candidate cells that produce antibodies with high affinity and specificity. The core principle of single B cell screening involves using flow cytometry or microfluidic platforms to isolate an......

• • High Throughput Screening of Drugs

  High throughput screening of drugs is a methodology that leverages automated technologies and large-scale assay systems to rapidly evaluate the interactions between thousands of compounds and biological targets within a short time. It represents a critical step in modern drug discovery pipelines. Through high throughput screening, researchers can efficiently identify candidate molecules with biological activity against specific targets from vast compound libraries. This technology significantly improv......