Resources

Proteomics Databases



Metabolomics Databases

• • IP-MS Protocol: From Antibody Capture to LC-MS/MS

  A practical IP mass spec protocol guide covering antibody qualification, lysis and wash design, controls, LC-MS/MS filtering, and project checkpoints.

• • AP-MS Workflow: From Tagged Bait Design to Interactome Interpretation

  A step-by-step technical guide to the AP-MS workflow covering tagged bait design, affinity purification, controls, LC-MS/MS filtering, and project planning.

• • AP-MS vs IP-MS: How to Choose the Right Interactome Workflow

  A focused comparison of AP-MS versus IP-MS for interactome studies, covering antibody versus tag capture, controls, artifacts, and decision criteria.

• • Planning an Affinity Purification Mass Spectrometry Project: Bait Design, Controls, Sample Preparation, and Validation Strategy

  A project-planning guide for AP-MS covering bait design, control architecture, sample preparation decisions, and validation strategy before LC-MS/MS.

• • Endogenous IP-MS vs. Tagged Pull-Down MS: Choosing the Right Affinity Purification Strategy for Protein Interaction Studies

  A comparison of endogenous IP-MS and tagged pull-down MS to help choose affinity purification strategies for physiological discovery or controlled binding studies.

• • Why AP-MS Results Contain Background Proteins: Controls, Replicates, and Filtering Strategies for Confident Interaction Analysis

  A problem-solving guide to background proteins in AP-MS, covering common sources and how controls, replicates, and filtering improve interaction confidence.

• • Affinity Purification Mass Spectrometry: How AP-MS Reveals Protein Interaction Networks from Bait-Enriched Samples

  A technical guide to how AP-MS converts bait-enriched samples into ranked protein interaction network candidates, including controls, limits, and design points.

• • Native MS vs. Intact Mass, SEC-MALS, and HDX-MS: Which Method Answers Your Protein Structure Question?

  A comparison of native MS, intact mass, SEC-MALS, and HDX-MS to help match each method to stoichiometry, identity, oligomer, or conformational questions.

• • High-throughput: Affinity purification mass spectrometry

  Learn how high-throughput affinity purification mass spectrometry scales multi-bait AP-MS panels through standardized controls, batch LC-MS/MS, and integrated interactor mapping.

• • How AP-MS Works?

  A step-by-step technical guide explaining how AP-MS works, covering bait capture, washing, elution, LC-MS/MS identification, controls, and common workflow failure points.